Protein Info for Sama_0541 in Shewanella amazonensis SB2B

Annotation: serine/threonine protein kinase, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 606 PF00069: Pkinase" amino acids 46 to 257 (212 residues), 70.3 bits, see alignment E=1.8e-23 PF07714: PK_Tyr_Ser-Thr" amino acids 50 to 188 (139 residues), 36.1 bits, see alignment E=4.7e-13

Best Hits

KEGG orthology group: K08282, non-specific serine/threonine protein kinase [EC: 2.7.11.1] (inferred from 100% identity to saz:Sama_0541)

Predicted SEED Role

"Protein kinase"

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S2Z5 at UniProt or InterPro

Protein Sequence (606 amino acids)

>Sama_0541 serine/threonine protein kinase, putative (RefSeq) (Shewanella amazonensis SB2B)
MSAQTPQLQHFYISEEQSIYLLKADDARKHKAWVRLCKQQLSKLGYRDIEFIGKGAYGFV
FAGINEASEAHVFKFSRITLPQQIQDRLEEEAFMLSHCRHPNVPPLVKFERVGKQGILVM
ARAPGEELEQLCRRRGALPIPMIMSIARQLADLLVYLRTGRPLVHGDIKPSNLVYDETTG
HLSLIDWGSAVFAQRDELGRPVEEHVMNLLSSDQQHTNARMGDVYFIGDEQLSGALSSPR
FDEQGVAATLYALASGQASRFGSRVIPPTSIGLPMELARTLEAMLSDDAQTRNRGGDYFL
RSMRHSHRLLLPDIPRPEAMAEIPVWVQNRGKEVDTVSYSSRKSFLREHNADEPIARVDD
VQLDKYYRNFLAGMGDTEKGFIAAVGRLGQYPIVGGLALHWQQDGVFIDSNLALHDATLK
QALVQAVNNMVTLARGIGRLGTFKACFFNARDTLHISRDPVSGTFVASPAQQLPFEVGDV
PMLEDKSRLHSYFEDGKDPDENLELPAEIMTELGWLNQIHHTGCIIFEALGDHLKIHSYL
KLLNPRKQAAFRASLDRILHHVDKIHGNGVSGFMKLPYKNTRRFAKISTKPEAFYPKDPR
QLHSET