Protein Info for Sama_0523 in Shewanella amazonensis SB2B

Annotation: sensory box sensor histidine kinase/response regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1179 transmembrane" amino acids 22 to 42 (21 residues), see Phobius details amino acids 54 to 71 (18 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 131 to 149 (19 residues), see Phobius details amino acids 168 to 188 (21 residues), see Phobius details amino acids 200 to 227 (28 residues), see Phobius details amino acids 247 to 267 (21 residues), see Phobius details amino acids 288 to 310 (23 residues), see Phobius details amino acids 334 to 363 (30 residues), see Phobius details amino acids 385 to 407 (23 residues), see Phobius details amino acids 418 to 441 (24 residues), see Phobius details amino acids 448 to 469 (22 residues), see Phobius details amino acids 480 to 495 (16 residues), see Phobius details amino acids 503 to 521 (19 residues), see Phobius details PF00474: SSF" amino acids 55 to 456 (402 residues), 26.2 bits, see alignment E=9.6e-10 PF12860: PAS_7" amino acids 643 to 756 (114 residues), 147.2 bits, see alignment E=5.4e-47 PF00512: HisKA" amino acids 791 to 854 (64 residues), 38.1 bits, see alignment 3.2e-13 PF02518: HATPase_c" amino acids 900 to 1033 (134 residues), 78.8 bits, see alignment E=1e-25 PF00072: Response_reg" amino acids 1061 to 1175 (115 residues), 39.4 bits, see alignment E=1.5e-13

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0523)

Predicted SEED Role

"Sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S2X7 at UniProt or InterPro

Protein Sequence (1179 amino acids)

>Sama_0523 sensory box sensor histidine kinase/response regulator (RefSeq) (Shewanella amazonensis SB2B)
MAGYWNIILGFILLAWLSVDTWWISVISIAYLAVLFIVAQWGQNQPFGQWRKRPWVYSLS
LGVCCTSWAFYGTVGQAATTGAWLAPIYIGSIVCLVLAWPMLMRTLHIVKSQNLTSIADF
IACRFDRSPKIAASVAMVSLLGTIPYIALQLRAISTSFDLLTGTFQSGISTAFIVTIVLI
IFSILFGTRQLSASKQNQGLVLAIAFSSVVKLLALTTVGIFATFYIFDGFSDLLTRGQAL
PTSKDANSLYFVLSQILLGAITIYALPQEFHMMMIENHHAKELKSARWMVPLYLLLMNAF
ILPIALAGQLSFPGGSVDADTYVLTLPLFYQQAWLGVLVYLGGLAAATAMVIVAAIVLST
MISTEILTPLLLRLPRFSSQQTPQLAGILLNLRRIAIAAILLSAFAFERYIDQQNHLASI
GLLSFVLLSQFAPAAIGALYWRRANTQGAFWGMLLGSLVWLYTLLLPATFPDANWVIHGP
WHIGWLAPHALFGLNGLDNISHGLFYSLLVNIGSFVLISHFREQSVGELLQADVFVNRKQ
LQLERHLSVSDLASLLHRFINKEEADALMAKARQLGSELSSRREELVDYTRLKLSGVLGS
ASTRMVMNAASRAQQVPLEDVVSIVDEANQIFEFNRELLQSGVENIEQGISVVDADMRLV
AWNKRYIELLDYPKDYVKAGIPIEKLLRYNIERGIIVGDEAHELVEKRLAHMRSGSPHHF
QRTMHDGRVLEIRGQAMPGGGFVSTFSDITAHIQAEKALQQANETLEKRVESRTRELAKA
KAEAEAANSSKTRFLAAASHDLMQPFNALTLFTEMLKQRVTSTELQDLATHIEDSLNVVE
SLLSDLVEISRLDSSSLKTEQSQFAIDDLLSTLVNEFRVLSKQQGIEFGYQFSSCFVQSD
QRLLRRIIQNFLSNAFHYSPAGALNQIQSATRVKLEGGESLTSDVEFMPRVVLGVRRRQD
SLLIQVWDNGPGIPAEKQQAIFGEFERLEQTREIPGLGLGLAICDRIAKLLGIRIYLHSE
LGKGTCFSVEVPRIRQQKPAGNVVKLRRDDEAIGDSFDIQVLVIDNDELMLKAISSLLLG
WGCKVLTARDKASALAQLEVSKPPRLILADYHLDDDQNGVSLVQSLLEHPRLLQARPTCI
ICSADPSEAVRQHTSSANFGFVRKPVKATALKRLIKQLS