Protein Info for Sama_0499 in Shewanella amazonensis SB2B

Annotation: HAD superfamily hydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 204 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 16 to 168 (153 residues), 38.5 bits, see alignment E=7.7e-14 PF12710: HAD" amino acids 17 to 124 (108 residues), 32.9 bits, see alignment E=1.4e-11 PF13419: HAD_2" amino acids 17 to 172 (156 residues), 60.9 bits, see alignment E=2.7e-20 PF00702: Hydrolase" amino acids 69 to 168 (100 residues), 46.1 bits, see alignment E=1.2e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0499)

Predicted SEED Role

"Predicted phosphatases"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S2V3 at UniProt or InterPro

Protein Sequence (204 amino acids)

>Sama_0499 HAD superfamily hydrolase (RefSeq) (Shewanella amazonensis SB2B)
MSRRAEYPEWLADIRAVVFDLDGTLAHSNPDFPAIRQALGLSAGEDILAHIAGLPAAKQA
GAMATVHHYEMAASHRAEWIGGAAELLQFVQQKTLPTAILTRNMRQAAELTLSRLGLSVE
VLLTREDAPAKPDPAGLIHIMDIWRLEPTQVLYVGDYLFDLQTARGAGCRSALYCPDGKP
DYGDMADLLVPCYFELIDLWRGAE