Protein Info for Sama_0170 in Shewanella amazonensis SB2B

Annotation: general secretion pathway protein E (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 520 TIGR02533: type II secretion system protein E" amino acids 35 to 517 (483 residues), 740.5 bits, see alignment E=4.1e-227 PF22341: GSPE_N1E" amino acids 36 to 99 (64 residues), 78.9 bits, see alignment E=2.5e-26 PF00437: T2SSE" amino acids 136 to 515 (380 residues), 531.3 bits, see alignment E=1e-163

Best Hits

Swiss-Prot: 70% identical to GSPE_VIBCH: Type II secretion system protein E (epsE) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02454, general secretion pathway protein E (inferred from 100% identity to saz:Sama_0170)

Predicted SEED Role

"General secretion pathway protein E"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S1X5 at UniProt or InterPro

Protein Sequence (520 amino acids)

>Sama_0170 general secretion pathway protein E (RefSeq) (Shewanella amazonensis SB2B)
MSDINQGEVLERLSDELGVEAETQVDEAFRSNSRERLPFAFAHRFGLVLAKDEQGVLGLY
YTDKTPLAALLEVRRYAGEAVPLQRLEASAFEARLTQAYQANSSEAQQLMEDIGNEMDLF
TLAEELPQTEDLLEGDDDAPIIRLINALLSEAIKEEASDIHIETYEKQLVVRFRVDGVLK
EVLKPNRKLSSLLVSRIKVMARLDIAEKRVPQDGRISLRIGGRAVDVRVSTMPSSHGERV
VLRLLDKNAGNLDLAQLGMTETIREQFDELIRKPHGILLVTGPTGSGKSTTLYAGLTEIN
SRDTNILTVEDPIEYELEGIGQTQVNTKVDMTFARGLRAILRQDPDVVMIGEIRDLETAQ
IAVQASLTGHLVISTLHTNTASGAITRLQDMGVEPFLVSSSLLGVLAQRLVRTLCPSCKA
PHVPDERERELLGIGGGDAVIYRATGCKACGHNGYRGRTGIHELLLVDDTVRELIHGGRG
ELAIEKYIRQSVPSIRHDGMQKVLAGITTLEEVLRVTREE