Protein Info for Sama_0120 in Shewanella amazonensis SB2B

Annotation: molybdopterin biosynthesis MoeA protein, putative (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 599 PF03205: MobB" amino acids 13 to 146 (134 residues), 163.7 bits, see alignment E=4.4e-52 TIGR00176: molybdopterin-guanine dinucleotide biosynthesis protein B" amino acids 13 to 173 (161 residues), 137.9 bits, see alignment E=3e-44 PF03453: MoeA_N" amino acids 202 to 360 (159 residues), 137 bits, see alignment E=9.7e-44 TIGR00177: molybdenum cofactor synthesis domain" amino acids 370 to 506 (137 residues), 102.1 bits, see alignment E=2.7e-33 PF00994: MoCF_biosynth" amino acids 373 to 510 (138 residues), 105.5 bits, see alignment E=4e-34 PF03454: MoeA_C" amino acids 527 to 595 (69 residues), 55.3 bits, see alignment E=1.2e-18

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 100% identity to saz:Sama_0120)

Predicted SEED Role

"Molybdopterin-guanine dinucleotide biosynthesis protein MobB / Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S1S6 at UniProt or InterPro

Protein Sequence (599 amino acids)

>Sama_0120 molybdopterin biosynthesis MoeA protein, putative (RefSeq) (Shewanella amazonensis SB2B)
MTTAFRNPLPVPVLGFCAYSGTGKTTLLLKLIPELNRRGLKLAVVKHAHHDFDVDIPGKD
SYELRKAGARQMLVASHVRWALMTEDARDSDPELPHLLNQIEADKVDIVLVEGFKKLSLP
KIELHRAAHGKPFIHTQDPDILAVACCDDTQLPSDLPRLDINNVAEIADFVQQYIANWCP
ATPSLPLAPACGCEADMSKTLSVRQGMDAILAKVVPVSETDLAPLDELDGRVLACDAISP
VDVPQQTNSAMDGFAFRFADPMPDALNIVGASFAGHGFADTLKPGEAVRIMTGAPLPAGA
DTVQPRELADDRGDTVSLQGKLEVGQHVRLAGEDITKGAVALGAGERIDAAATGLLASLG
FDKVQVKRRPRVAVFSTGDEVSAPGEPLAPSCIYDSNRFTIKNMAKRLGCEVIDLGIIED
SEASLMAALEQGASCADVVISSGGVSVGDADYIKTALEKLGQIGFWRINMRPGRPLAFGE
INRALFFGLPGNPVAVMVSFLQFVQPALRKLAGENQYQPRFIPAITDEVLRSRIGRTEFF
RGIYHLGDDGQLHVKTTGAQGSGMLSSMVKGNCLIVLAEPDEQLAIGSRVYIQPFADLL