Protein Info for Sama_0067 in Shewanella amazonensis SB2B

Annotation: signal transduction histidine kinase-like protein protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1021 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 176 to 196 (21 residues), see Phobius details TIGR00229: PAS domain S-box protein" amino acids 258 to 368 (111 residues), 28 bits, see alignment E=1e-10 PF08448: PAS_4" amino acids 262 to 360 (99 residues), 40.5 bits, see alignment E=8.5e-14 PF00512: HisKA" amino acids 397 to 461 (65 residues), 67.1 bits, see alignment 3.4e-22 PF02518: HATPase_c" amino acids 508 to 623 (116 residues), 99.6 bits, see alignment E=4.5e-32 PF00072: Response_reg" amino acids 775 to 888 (114 residues), 88 bits, see alignment E=1.4e-28 PF01627: Hpt" amino acids 932 to 1014 (83 residues), 43.8 bits, see alignment E=7.7e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to saz:Sama_0067)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A1S1M3 at UniProt or InterPro

Protein Sequence (1021 amino acids)

>Sama_0067 signal transduction histidine kinase-like protein protein (RefSeq) (Shewanella amazonensis SB2B)
MKWLGGGKSLGYKLNMATALLAIGVCLLVGLYYQNDVSERIRDVARHEMADLVNSLNLAL
ETKANRSDVQRVMGALSTKESIRRISLIEGEKITADNHAQHIGRTVAESFGSQVQQLIRN
TRTKNSDDPFLEKDGVIHQTALLYLISPERQRLRPFVLYVAYDPAALEQAAQKGFMEFIL
IQSLGFMLLLFINTLVQQKVVLGPINAIRRQIEADPQSELALKADDELGLLVESYNASIR
QRIMQAKELEDSRRYIDTVINVIPVQLAYVDASRCYRFINRRYLVWLGKSEAEVLGRSVT
DVLPPPVEELIVPYQLRALQGNQQVFDAEFDDKYFQATYVPDVTNDGEVVGFFACVEDLT
PIKANERKIESYALELEHKNADLVEAREKAEAASRIKADFLACMSHEIRTPMNGVLGILS
LLEKTELSIQQKHYLDVASTSAESLLTLLNDILDFSKIESGKFEIDEVPFDLIQLLDDFI
QPFAIRAEAKGLKLLLDISGIHLRWVRGDPGRIRQVLVNLVSNAIKFTEVGWIAVRVQAS
EDTANGVSLMVSIEDTGIGISKDKQEVLFSPFTQADSTTTRHFGGTGLGLSIAKRLCELM
DGDIRVISAEDAGSTFKFHLRLKSEAASGAEWPPALNCRAPLLAGELGASERMLFELLDS
WQLRPALLESNTELAQTPALAAADWLIYSVPEHLVSITQELQKMAAFATEKGLKFLAIIS
HRQQIGLAPTILSSCHYLCRPMQALKLVDILSDSDGNDVVLPDDTQSQLNDSAQILLVED
NKVNQMVALGMLRNLGLKHVEVVTNGLQALAALQHRQYDLILMDCLMPEMDGYQATQAIR
KGEAGQKHKDIKIVAMTANAMKGDRETCLEAGMNDYIAKPLHQAEVARVLERYIPLDSTS
CAPSNPLSADTLLFDRHCALELMSGDSELLGDILKVFAEEMAVYLEAFESAMGRRDFAAV
RTAVHAIKGAAGNLCMSPLAGVAKEMEMAARRLDWVYLEAHQAEFIDVLRRTLEQSQLPT
A