Protein Info for Shew_3855 in Shewanella loihica PV-4

Name: gidB
Annotation: glucose-inhibited division protein B (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 234 PF02527: GidB" amino acids 48 to 227 (180 residues), 198.8 bits, see alignment E=5.3e-63 TIGR00138: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG" amino acids 53 to 229 (177 residues), 175 bits, see alignment E=6.4e-56

Best Hits

Swiss-Prot: 100% identical to RSMG_SHELP: Ribosomal RNA small subunit methyltransferase G (rsmG) from Shewanella loihica (strain ATCC BAA-1088 / PV-4)

KEGG orthology group: K03501, ribosomal RNA small subunit methyltransferase G [EC: 2.1.1.170] (inferred from 100% identity to slo:Shew_3855)

MetaCyc: 59% identical to 16S rRNA m7G527 methyltransferase (Escherichia coli K-12 substr. MG1655)
RXN-11578 [EC: 2.1.1.170]

Predicted SEED Role

"rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.170

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QJS0 at UniProt or InterPro

Protein Sequence (234 amino acids)

>Shew_3855 glucose-inhibited division protein B (RefSeq) (Shewanella loihica PV-4)
MTGMGGQALPIPATRLHNIPLFIEDTPVLAAQLDSYLADMQMTATPKQKQQLLDFVAMLA
KWNKAYNLTSVRDPEQMLIRHIMDSLAASPHLVGERFIDVGTGPGLPGIPLAIMNPDKEF
VLLDSLGKRIRFQKQVQFELAIGNISSVESRVEAYQPEEKFDGVLSRAFASIQDMLQWCH
HLPKPTGCFYALKGQLSDEEMANMPEGFTLTDVFELKVPRLDEQRHLLRVVKAA