Protein Info for Shew_3806 in Shewanella loihica PV-4

Annotation: phosphoglyceromutase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01307: phosphoglycerate mutase (2,3-diphosphoglycerate-independent)
  • amino acids 7 to 510 (504 residues), 742.6 bits, E=9.6e-228
• PF01676: Metalloenzyme
  • amino acids 7 to 497 (491 residues), 289.1 bits, E=3e-90
• PF06415: iPGM_N
  • amino acids 84 to 299 (216 residues), 275 bits, E=4.2e-86

Best Hits

Swiss-Prot: 100% identical to GPMI_SHELP: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (gpmI) from Shewanella loihica (strain ATCC BAA-1088 / PV-4)

KEGG orthology group: K01834, phosphoglycerate mutase [EC: 5.4.2.1] (inferred from 100% identity to slo:Shew_3806)

MetaCyc: 66% identical to 2,3-bisphosphoglycerate-independent phosphoglycerate mutase (Escherichia coli K-12 substr. MG1655)
3PGAREARR-RXN [EC: 5.4.2.12]

Predicted SEED Role

"2,3-bisphosphoglycerate-independent phosphoglycerate mutase (EC 5.4.2.1)" in subsystem Entner-Doudoroff Pathway or Glycolysis and Gluconeogenesis or Glycolysis and Gluconeogenesis, including Archaeal enzymes (EC 5.4.2.1)

MetaCyc Pathways

• gluconeogenesis I (13/13 steps found)
• superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass (22/26 steps found)
• superpathway of glycolysis and the Entner-Doudoroff pathway (15/17 steps found)
• Bifidobacterium shunt (13/15 steps found)
• superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle (18/22 steps found)
• Rubisco shunt (9/10 steps found)
• superpathway of glucose and xylose degradation (14/17 steps found)
• glycolysis I (from glucose 6-phosphate) (11/13 steps found)
• 1-butanol autotrophic biosynthesis (engineered) (21/27 steps found)
• superpathway of anaerobic sucrose degradation (15/19 steps found)
• photosynthetic 3-hydroxybutanoate biosynthesis (engineered) (20/26 steps found)
• glycolysis II (from fructose 6-phosphate) (9/11 steps found)
• glycolysis III (from glucose) (9/11 steps found)
• ethene biosynthesis V (engineered) (19/25 steps found)
• photorespiration II (8/10 steps found)
• homolactic fermentation (9/12 steps found)
• hexitol fermentation to lactate, formate, ethanol and acetate (14/19 steps found)
• superpathway of N-acetylneuraminate degradation (16/22 steps found)
• glycolysis IV (7/10 steps found)
• glycolysis V (Pyrococcus) (7/10 steps found)
• glycolysis VI (from fructose) (7/11 steps found)
• Entner-Doudoroff pathway III (semi-phosphorylative) (5/9 steps found)
• glycerol degradation to butanol (10/16 steps found)
• superpathway of hexitol degradation (bacteria) (10/18 steps found)
• gluconeogenesis II (Methanobacterium thermoautotrophicum) (8/18 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (21/56 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Biosynthesis of alkaloids derived from shikimate pathway
• Biosynthesis of alkaloids derived from terpenoid and polyketide
• Biosynthesis of phenylpropanoids
• Biosynthesis of plant hormones
• Biosynthesis of terpenoids and steroids
• Glycolysis / Gluconeogenesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.1 or 5.4.2.12

Sequence Analysis Tools

See A3QJM4 at UniProt or InterPro

Protein Sequence (514 amino acids)

>Shew_3806 phosphoglyceromutase (RefSeq) (Shewanella loihica PV-4)
MTTRKRPLALLILDGWGYRENTHMNAVYHANTPVLDRLNKEYPNSLISGSGLDVGLPDGQ
MGNSEVGHINIGSGRVVYQELTRIGKSIEDGEFDSNPAFVDAVDKAIAADGAVHIMGLLS
PGGVHSHESHIQAMCKMAVARGAKQVYLHAFLDGRDTPPRSAKGSLQAFNELFAELGTGR
IASLIGRYYAMDRDNRWDRVSQAYELITQGKALHLYQDAVEALDAAYGRDENDEFVASSA
ITDADGQVATLNDNDALIFMNFRADRARQITRSFVDPGFDGFERAVTPKINFVMLTEYAA
DIKAPVAYPSVDLVNTLGEVLQNNGKTQLRISETEKYAHVTFFFNGGKEEPFEGEDRILI
QSPKVATYDLQPEMSSTELTDKLVEAIESTQYDVIICNYPNGDMVGHTGNFDAAVKACEA
VDACIGRVVEALAKVDGECLITADHGNAEQMTDEQTGQAHTAHTSELVPLIYVGRKGEIA
PNGRLSDLAPTMLTLMGQTVPSEMTGHSIITLSE