Protein Info for Shew_3632 in Shewanella loihica PV-4

Annotation: sulfatase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 662 transmembrane" amino acids 13 to 35 (23 residues), see Phobius details amino acids 56 to 76 (21 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 144 to 162 (19 residues), see Phobius details amino acids 174 to 192 (19 residues), see Phobius details PF00884: Sulfatase" amino acids 285 to 555 (271 residues), 178.9 bits, see alignment E=7.8e-57

Best Hits

Swiss-Prot: 57% identical to Y1246_HAEIN: Uncharacterized protein HI_1246 (HI_1246) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3632)

Predicted SEED Role

"Phosphoglycerol transferase I (EC 2.7.8.20)" (EC 2.7.8.20)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QJ50 at UniProt or InterPro

Protein Sequence (662 amino acids)

>Shew_3632 sulfatase (RefSeq) (Shewanella loihica PV-4)
MTTSHKKHGPMRAIVYFGLIALAITMLSRIGLGIWQADRVAAVDGWPHLLLQGLRVDFAT
LCWLWGIAALGTTIFGGDHIVGRGWKSVLRVWLTLGLWLMIFLELSTPSFIDEYGLRPNR
LYIEYLIYPKEVLSMLWTSRKGEIFLGLIVSTLSLWGGWRLSGRLLKEVVYPRWFWRPAI
GLLVIAVTLMGARSSLGHRPLNPAMVAFADDPLVNSLVVNSSYSLVFAIDQMAAEANASK
VYGKLEKSQIIDNIRKDSGRPLSAFTSESLPSVTYNQASFQGKPKNLVIILQESLGARFT
GYLGGLPLTPNIDALAQEGWAFNRLYATGTRSVRGIEAVTTGFTPTPARSVVKLGKSQTD
FFTIADLLKMNGYETQFIYGGESHFDNMRSFFLGNGFSDIVDQNDYKDPVFVGSWGVSDE
DLLKRANNEFEQFHKEGKPFFSLVFSSSNHEPFEFPDDRIELYDQPKQTRNNTAKYADYA
VGEFFKLAKASSYWKDTLFVVVADHESRVGGASLVPVEQFRIPAIIIGDGITPKMDQRVA
SQIDLAPTLLSLMGVSGSYPMLGRDLTKMDDDWPGRALMQYDKNMAYLRGDDVVILQPER
EPTGYAYDFASNTLTHKAQSDEMKQTALSWALWGSMAYQQQLYQTPQQSTALNTSSDEAS
IR