Protein Info for Shew_3573 in Shewanella loihica PV-4

Annotation: Fis family GAF modulated sigma54 specific transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 591 PF01590: GAF" amino acids 84 to 186 (103 residues), 45.2 bits, see alignment E=3.5e-15 PF00158: Sigma54_activat" amino acids 287 to 451 (165 residues), 218.3 bits, see alignment E=1.3e-68 PF14532: Sigma54_activ_2" amino acids 297 to 456 (160 residues), 66 bits, see alignment E=1.1e-21 PF07728: AAA_5" amino acids 307 to 426 (120 residues), 26.8 bits, see alignment E=1.2e-09 PF02954: HTH_8" amino acids 561 to 586 (26 residues), 38.1 bits, see alignment (E = 2.6e-13)

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_3573)

Predicted SEED Role

"Sigma-54 dependent transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QIZ1 at UniProt or InterPro

Protein Sequence (591 amino acids)

>Shew_3573 Fis family GAF modulated sigma54 specific transcriptional regulator (RefSeq) (Shewanella loihica PV-4)
MTIAPQTQAWLSDSWSRSQGAGLSEAKLPQELRLNAEALAERHHANKQLINLTKQHALPL
FNQMMAHSQSRLILSDRDGYVLCHWGVSRYSDKLANVALDVGVNWREEHKGTNAIGTALT
ARQTVAVIGEQHFIRHHRFMSCTASPIFSPEGELLGAIDITSEQQRHTQQTLVLIASLVQ
QIETALLCHLPGSHYRIDLAEQPSLITSGWQGIVVANVDGKLLGCNAMAKRLLHRPRIGD
DIDRHLGASWNSGEQVCQDQRLHLKTQQLVETRPSQLVSQQIGVRFRDPKLERAWQQANK
VVGRNIPLLICGETGVGKEQFVKKLHGQSTRAQRPLVAVNCAALPAELVESELFGYQAGA
FTGASRQGFEGKIRQADGGFLFLDEIGEMPLATQSRLLRVLQEREVVPVGGNRSYKVDIQ
VVAATHADLRQLVSEGAFREDLYYRLNGLQVSLPPLRQRADIERIIHKLHRRYRQAPQQL
CPQLLRRLLAHDWPGNLRELDNLMQVACLMADGDPELNWQHLPDTLQAQLQGPEQAGEQM
AACESELSLMVNANIVSSFHRFEGNVSRCAKHLGISRNTLYRKLKALGLKP