Protein Info for Shew_3518 in Shewanella loihica PV-4

Annotation: thioesterase superfamily protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13279: 4HBT_2
  • amino acids 14 to 127 (114 residues), 43.6 bits, E=3.8e-15
• PF03061: 4HBT
  • amino acids 21 to 100 (80 residues), 24.3 bits, E=3.3e-09

Best Hits

KEGG orthology group: K07107, acyl-CoA thioester hydrolase [EC: 3.1.2.-] (inferred from 100% identity to slo:Shew_3518)

Predicted SEED Role

"FIG002571: 4-hydroxybenzoyl-CoA thioesterase domain protein"

KEGG Metabolic Maps

• Benzoate degradation via CoA ligation
• Biosynthesis of plant hormones
• Biosynthesis of unsaturated fatty acids
• Fatty acid biosynthesis
• Limonene and pinene degradation
• Ubiquinone and menaquinone biosynthesis
• alpha-Linolenic acid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.2.-

Use Curated BLAST to search for 3.1.2.-

Sequence Analysis Tools

See A3QIT6 at UniProt or InterPro

Protein Sequence (144 amino acids)

>Shew_3518 thioesterase superfamily protein (RefSeq) (Shewanella loihica PV-4)
MKALLTTEMEMVIPFHDVDSMGITWHGNYLRYFEIARCQLLDEIDYGYRKMQASGYAWPI
IDLQIKYVQASTFEQRVKVIASLVEWENRLKITYQVRDAETNQRLTKGYTVQAAVEMESK
ELCLVTPDCFRDKIAHLLPSEAQA