Protein Info for Shew_3449 in Shewanella loihica PV-4

Annotation: cell division protein FtsZ (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 TIGR00065: cell division protein FtsZ" amino acids 8 to 326 (319 residues), 451.5 bits, see alignment E=1.2e-139 PF00091: Tubulin" amino acids 14 to 173 (160 residues), 179.2 bits, see alignment E=1.1e-56 PF12327: FtsZ_C" amino acids 222 to 316 (95 residues), 124.6 bits, see alignment E=1.7e-40

Best Hits

Swiss-Prot: 77% identical to FTSZ_ECO57: Cell division protein FtsZ (ftsZ) from Escherichia coli O157:H7

KEGG orthology group: K03531, cell division protein FtsZ (inferred from 100% identity to slo:Shew_3449)

Predicted SEED Role

"Cell division protein FtsZ (EC 3.4.24.-)" in subsystem Bacterial Cell Division or Bacterial Cytoskeleton (EC 3.4.24.-)

Isozymes

Compare fitness of predicted isozymes for: 3.4.24.-

Use Curated BLAST to search for 3.4.24.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QIL7 at UniProt or InterPro

Protein Sequence (391 amino acids)

>Shew_3449 cell division protein FtsZ (RefSeq) (Shewanella loihica PV-4)
MFEIMDSHSDEAVIKVIGVGGGGGNAVEHMVKHNIEGVEFVATNTDAQALRKSAAGTTIQ
LGRDVTKGLGAGANPEIGRLAAEEDRENIRSAIKGSDMIFIAAGMGGGTGTGAAPVVAEI
AREEGILTVAVVTKPFPFEGKKRMAYADQGIEMLAKHVDSLITIPNEKLLKVLGRGTSLL
DAFAAANNVLLGAVQGIAELITRPGLINVDFADVKTVMSEMGNAMMGTGVASGEDRAEEA
AEAAVASPLLEDIDLAGARGVLVNITAGMDMSIEEFETVGNHVKAYASDNATVVVGAVID
PEMSDELRVTVVATGIGAEKKPDIQLVSKPAPRPEPMPAPEVKIELPVEEAVPQAMGAGN
VVQVAQPAAAAAPKSDLDYLDIPAFLRKQAD