Protein Info for Shew_3097 in Shewanella loihica PV-4

Annotation: TonB-dependent siderophore receptor (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 723 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF07715: Plug" amino acids 70 to 167 (98 residues), 54.9 bits, see alignment E=1.2e-18 TIGR01783: TonB-dependent siderophore receptor" amino acids 71 to 720 (650 residues), 304.9 bits, see alignment E=6.9e-95 PF00593: TonB_dep_Rec_b-barrel" amino acids 251 to 693 (443 residues), 161.2 bits, see alignment E=7.8e-51

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to slo:Shew_3097)

Predicted SEED Role

"Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHL5 at UniProt or InterPro

Protein Sequence (723 amino acids)

>Shew_3097 TonB-dependent siderophore receptor (RefSeq) (Shewanella loihica PV-4)
MKLKPISLAIFCALSMATMPGHAENQTAPLDNDSQQDNLNIEKIEVRGRYVQGYNAHSVG
GASRLDLAIIDIPQSVSVITDAQLDDFQLNDINSALDSATGINVERIETDRTYYTARGFD
ITNFQIDGVGLPLTSGNNHADEDTAIYDRIEVIRGANGLMTGVGNPSATVNFIRKRPTSD
NQLKLQASYGSFNNARVEADASGRLNDNFAARVVAVKQQKDSYLDRYETDKSVLYAFIEA
NLSDDTSLSVSHSYINNDATGNNWGALPLYYTDGSPTNYDRSTNTSANWSNWQVIKNNTV
VELSHYFADDWRLRATYSHKSTDEDTELFYVYGTPDRETGLGLTGYGSEYDLDESHDLVD
LYVDGEFSLFGRDHQLVAGVNYAKVDYIDTSLYDYTTGNGFPAMPDLNDWDGNTPKPVFA
DSPRGSDVSAKQQAAYFTGRFNLFDGFHFIAGGRFNKWQAEGVSYDKVQDVEDSQFIPYL
GAVYRITPELVAYASYTETFKSQTEMDIDDNLLAPVTGESKEIGFKSELFDGRLIASLAY
FDIQQVNLAVPDPRTADLPPTDQRYIGADGINSKGYEFEVAGEVFDGLNLSLGFTDFDID
GNDDNAKIVAAYTPSRLLKFAATYDVAAIEGLSVGMNMRWQDDIYRDQGVVGDGFANAGE
AIITRQGAYAIVDLMARYQFNDNLQLSLNANNVTDEKYLNSLYWAQAFYGAPANYSATIT
WKL