Protein Info for Shew_2990 in Shewanella loihica PV-4

Annotation: TonB-dependent receptor (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 656 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF07715: Plug" amino acids 49 to 154 (106 residues), 79.5 bits, see alignment E=2.5e-26 PF00593: TonB_dep_Rec" amino acids 226 to 622 (397 residues), 129.8 bits, see alignment E=2.8e-41

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 100% identity to slo:Shew_2990)

Predicted SEED Role

"TonB-dependent receptor; Outer membrane receptor for ferrienterochelin and colicins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHA8 at UniProt or InterPro

Protein Sequence (656 amino acids)

>Shew_2990 TonB-dependent receptor (RefSeq) (Shewanella loihica PV-4)
MGTQPSKIALLLGACLAGSFPALAESSGTPGPVDETITVIGRTENTPINIAANVNVIDAA
AIELSGATNLTELLRGQSGIQVSDSNSGAVFAMRGFSASQAVNNTLILIDGRRLNNIDIA
APSISAIGLNQVERIEILSGSAGVLYGDQAVGGVINIITKAPKDNGGSLQLSGGSFDTFE
AKAEGSVAINDNWRLYGAANHLKSDNYRDHNASKTSSVLGRLQYDDEVQQFLAEASHYDN
HRELAAALNDDQLKQNPRQMGDLKQGDLFIDAYLHEMTTAARTGYQRQLNEAWALGADLN
YSDTLTTGLSTWNTSRRDTRSLLEFKPKAVANIKTDIGELKLVTGLDLSRGEATFSNRSN
VQKLASAYLQATVPLTESFSYVVGGRYAEVTDELVDASAYPNGIDLDQDAHAFELGLNYR
PSQQHRFYLRADDNFRFAKVDEQAYTPESIQGLKPQTGRSYEAGWDLLLERNTLRLSAYR
LDLEDEIVFDPSAETPAGGSFPGANVNADASRRYGVSADWDWQATQDLLLGLEYNYIDAE
FTEGANEGKALSWVAKNTGRGYVSYDVYEHLQLFAEAVYTGERYMEGDNANQGDKLDAYT
LANIAINYSRDAWLASLRVDNLLDKEYVSSGYFSTWGSGYYPGTGRALRLTASYRF