Protein Info for Shew_2982 in Shewanella loihica PV-4

Annotation: glucose-methanol-choline oxidoreductase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 PF00732: GMC_oxred_N" amino acids 96 to 326 (231 residues), 48.4 bits, see alignment E=1.1e-16 PF05199: GMC_oxred_C" amino acids 437 to 553 (117 residues), 81.3 bits, see alignment E=1e-26

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2982)

Predicted SEED Role

"Glucose-methanol-choline (GMC) oxidoreductase:NAD binding site" in subsystem Respiratory dehydrogenases 1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QHA0 at UniProt or InterPro

Protein Sequence (572 amino acids)

>Shew_2982 glucose-methanol-choline oxidoreductase (RefSeq) (Shewanella loihica PV-4)
MGLAAKGEAQAPQQFEVCIVGSGAGAGPIAYELVKAGIAVAVLEKGDWYTEQDFVKDEQL
PRHRVFRSKFDEERHVLELPDGEGGWRRETTAQFWGGNIVGGASNFMSGYFHRLKPSDFR
LASTFGAIPGANTVDWPISYEELEPYYAKVEQIVGVSGRVVKHPQLEPRSTLDFPFPPTA
EHPIAARFDKACETLKLHPLPMARAILSRPFKQRLSCEYSGYCGSYGCHSGAKGSSRAAL
LNDAVASGNCRIITRAKVYRLNTDAQGRVSSADYFDASGQSRRIMAKAFVVACYAIESTR
LLLASPGEKHPKGIGNRFDQLGKNLHCCAGGTGHGVFKLDRLPADAAKGLKQRGPFFNRA
LQDWYVIDDKTAFDKPVKGGTLDFVFDPPSPTSEANALKWQQGNLLWGTPLKQKLKAHFT
QSRDFKFEVFCDWLTNDNCFVTLDDEERDKWGQPVARVRAGFHPHDLKVAQYLVDRGVEV
MKAMGADEAWGNVFSDPTANLVAGGCRFGKDPKTSVLNPDCQVHDCDNLYVTDGAFMPNG
GSVTPTLTIYANAFRVADKLLARLASASETST