Protein Info for Shew_2892 in Shewanella loihica PV-4

Annotation: major facilitator transporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 472 transmembrane" amino acids 21 to 43 (23 residues), see Phobius details amino acids 55 to 72 (18 residues), see Phobius details amino acids 93 to 110 (18 residues), see Phobius details amino acids 122 to 142 (21 residues), see Phobius details amino acids 162 to 181 (20 residues), see Phobius details amino acids 193 to 213 (21 residues), see Phobius details amino acids 269 to 293 (25 residues), see Phobius details amino acids 310 to 328 (19 residues), see Phobius details amino acids 335 to 356 (22 residues), see Phobius details amino acids 362 to 386 (25 residues), see Phobius details amino acids 398 to 417 (20 residues), see Phobius details amino acids 425 to 446 (22 residues), see Phobius details PF13000: Acatn" amino acids 22 to 206 (185 residues), 30.4 bits, see alignment E=1.6e-11 PF07690: MFS_1" amino acids 24 to 386 (363 residues), 55 bits, see alignment E=6.8e-19

Best Hits

KEGG orthology group: K08218, MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG (inferred from 100% identity to slo:Shew_2892)

Predicted SEED Role

"AmpG permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QH10 at UniProt or InterPro

Protein Sequence (472 amino acids)

>Shew_2892 major facilitator transporter (RefSeq) (Shewanella loihica PV-4)
MIASRVSRLRDALTIYFHKRVLILLFLGFSAGLPLMLVFSTLSFWLREAGIDRTAIGYFS
WIALAYGFKWAWSPLVDRMSLPFFTQILGRRRGWMLFAQMLLVLAILGMSQSDPLADLER
LALFALMVAFASATQDIVIDAFRIESAPQKMQAALAAAYQVGYRSAMIVATAGALTIAAW
VDPNSESYDLASWQTAYLVMAGLMFIGIFTTLLSSEPKVEAKEADQIESDLKQCLSERYP
RPVAAAASWLYTASILPFIDFFKRYGRSAILILLLISCYRISDIVMGIMANVFYVDMGFS
KTEIATLSKVYGLIMTLVGAGAGGMLLARYGTMKILFLGAFMVAVTNLLFAYQAMIGYNL
ELLTVVISIDNFSAGVATAAFIAYLSSLTSSGYSATQYALLSSIMLLFPKFVAGFSGQYI
DAYGYVNFFVAASVIGFPVLGLIVLVQKYAPHPNGDEQAESLDSSNGQQARD