Protein Info for Shew_2809 in Shewanella loihica PV-4

Annotation: alpha/beta hydrolase fold (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 PF00561: Abhydrolase_1" amino acids 36 to 181 (146 residues), 36.8 bits, see alignment E=5.5e-13 PF12697: Abhydrolase_6" amino acids 38 to 238 (201 residues), 31.6 bits, see alignment E=4.2e-11 PF12146: Hydrolase_4" amino acids 47 to 141 (95 residues), 30.1 bits, see alignment E=4.7e-11

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2809)

Predicted SEED Role

"Esterase/lipase/thioesterase family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGS7 at UniProt or InterPro

Protein Sequence (308 amino acids)

>Shew_2809 alpha/beta hydrolase fold (RefSeq) (Shewanella loihica PV-4)
MFSVSTLIQESRFIPYRQGQLHLRLLKRPDADMSRPPILMLHGAMSNGRVFYSDKGRGLG
CYLAEAGFVVYVLDTLGRGLSTPKLSTGASHGQGEVIREQLPLVQHYILSQHPEAHKVHW
CAHSWGGVLMASAIARFDFFQTSVASLLTFGSKRAIKVRSLKKWLMVDLVWNKLAPAIAA
GHGYLAADRWRMGMDNETRASLSQSIDWVRGEWIDHDDGFDYAKAAIALGAKQGWPKSWF
IAGKGDQVLGNPADVQRMIKECHIKPVTYTLLSKANGNRHDYGHAEMLTHKDATEDHFPQ
VLSWYQAL