Protein Info for Shew_2797 in Shewanella loihica PV-4

Annotation: trimethylamine-N-oxide reductase c-type cytochrome TorC (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details TIGR02162: trimethylamine-N-oxide reductase c-type cytochrome TorC" amino acids 6 to 392 (387 residues), 501 bits, see alignment E=1.4e-154 PF03264: Cytochrom_NNT" amino acids 15 to 187 (173 residues), 242.5 bits, see alignment E=4.6e-76

Best Hits

KEGG orthology group: K03532, trimethylamine-N-oxide reductase (cytochrome c) 1, cytochrome c-type subunit TorC (inferred from 100% identity to slo:Shew_2797)

Predicted SEED Role

"Cytochrome c-type protein NapC" in subsystem Nitrate and nitrite ammonification or trimethylamine N-oxide (TMAO) reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGR5 at UniProt or InterPro

Protein Sequence (392 amino acids)

>Shew_2797 trimethylamine-N-oxide reductase c-type cytochrome TorC (RefSeq) (Shewanella loihica PV-4)
MKWFITLWRTLNKPAKTLTLGAISLSAFLMGIIFWGGFNTALEATNTEAFCISCHSMESK
PYQELQSTVHWSNHSGVRATCPDCHVPHNWSRKIGRKIEASHDMWGWLLQTVNTEEKFEA
KRLEMASREWKRFDRDNSLACKNCHNYDSMKWDEMSKLAQKQMKRAAELDQSCIDCHKGI
AHKLPDMGTSRAPELIAQVGSGESSLAIGESYFSALTKPLFFNEKTDVEAGTLNIATKVK
VLEVKGQRAKVGIDGWRKKIGAGRVIYFDFGMNILSAQLSKDAALEPGVMQVFEEQQDPL
TGLIWQRVEAQIWVDGDYLVKDLQPLWDYARDTYSSSCSVCHTQPDEAHFDANTWPGMFQ
GMIAFVNMDQDTQALVQKYLQEHSSTFATSAH