Protein Info for Shew_2667 in Shewanella loihica PV-4

Annotation: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1200 1300 1400 1500 1600 1700 1800 1928 PF00109: ketoacyl-synt" amino acids 21 to 298 (278 residues), 119.1 bits, see alignment E=3.9e-38 amino acids 505 to 770 (266 residues), 58.1 bits, see alignment E=1.6e-19 PF02801: Ketoacyl-synt_C" amino acids 306 to 423 (118 residues), 115.2 bits, see alignment 2.6e-37 PF07977: FabA" amino acids 1335 to 1469 (135 residues), 142.7 bits, see alignment 9.3e-46 amino acids 1785 to 1918 (134 residues), 129.3 bits, see alignment 1.2e-41

Best Hits

Predicted SEED Role

"omega-3 polyunsaturated fatty acid synthase subunit, PfaC"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QGD5 at UniProt or InterPro

Protein Sequence (1928 amino acids)

>Shew_2667 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ (RefSeq) (Shewanella loihica PV-4)
MPSNEAPSAKQVPPKTRGHGKIAIVGLANLYPDAKTPKQFWQNLLDKRDSRTQLSDDKLG
AHLADFRGEQGEADRFYCDKGGYIEDFHFNPYGYKLPPEQLQGMDDSLLWALDTSRNALL
DAGIALDSPQLSRCGIIMGTLSFPTAKSNELFLPLYHKAVEKALKQKLACPDFSLSDYNA
HSPAATTLDVANGAIAHNASKLVADALGLGRVQLSLDAACASSVYSLKLACDYLNTGKAD
LMLAGAVSGADPFFINMGFSIFHAYPEHGFSAPFDRNTKGLFAGEGAGVLALKRLEDAER
DNDKIYAIVSGIGLSNDGKGQFVLSPNSKGQVKAFERAYRHSGVAPKQIEVIECHATGTP
LGDKVELASMEQFFAPGLEGASAPMIGSAKSNLGHLLTAAGMPGIMKMIFAMNQGQLPPS
INLSEAIESPNGLFGAHTLPRQVTPWPIKADNAARLAGVSVFGFGGCNAHLLLESYTPTE
CEPSTTATSPQLTAPCHNGSTPQFVISGIAAHLGPLGSINALDTCIRQEQEAFVPLPPAR
WKGLDQHPELLAQFGLDSAPRGAYVDSFELDFLRFKLPPNEDDRLIGQQLMLMKVADEAI
RDAALQPGQKVAVLVAMETELELHQFRGRVNLHTQLKQSLDAMGASLSDSQYRELEALAM
DSVLDAAKLNQYTSFIGNIMASRIASLWDFSGPAFTISAGEQSVGRALDVAENIMVQEQL
DAVVIAAVDLCGSLEQVMLKNAIAPVANQSHPNGWRLAEGAGALVLETSSHQSQRGASAY
GKIESLNFGPQHQLARLCDELLTLNGTDAEQISLVEMNVAPCSQHQPQQLIAQLPTAQAR
LVQSDQQLGHSFAAAGMTSLIATLLRMTQENADNALVANFSEDQSALLHLTQTHTQRGAL
TQRLDQDLTTHEGRSLIKRVTLGGRGIIEHILTQPLTQLSALQDKLAAANGQGQTKPKKV
SKLISYLGQVNSNTTQASQFATPSMTGGATGNLPTMTQHSAQPPGSPISNPDLSAFHDNQ
QKARQAHLAFLKSRESGLKVADLLLKQQLAQAIGSPSTPASASSVTQMPLKPRHDLVAPY
RAPVPAHKPCIWDYHDLVEYAEGDIAKVFGPDYSVIDGYSRRVRLPTTDYLLVSRVTKLD
AKLGEYKPSTMTTEYDIPVDAPYLVDGQIPWAVAVESGQCDLMLISYLGIDFENKGERVY
RLLDCTLTFLGDLPRGGDTLRYEIKINNFARNGDTLLFFFSYECFVGDTMILKMDGGCAG
FFTDAELADGKGVIRTEEELLARSRATKQIFNPLLDCPRTQFSYGDIHKLLSADIQGCFG
PSHAGPAQPSLCFASEKFLMIEEVSKVERSGGAWGLGLVEGHKQLEPNHWYFPCHFKDDQ
VMAGSLMAEGCGQLLQFYMLHLGMHTQTQNGRFQPLENASQKVRCRGQVIPQSARLTYRM
EVTEIGFSPRPYAKANIDILLNGKVVVDFQNLGVMIKEEAECTRYPELESSDASSAQAKA
NQGASANAPLMTNAPLMAQVPDLSAAPNKGVIPLTHVEAPVTPDYPNRVPDTVPFTPYHL
FEFATGDIEKCFGPEFAIYRGMIPPRTPCGDLQLTTRVIEVNGQRGDFKRPASCIAEYEV
PRDAWYFDANSHQALMPYSVMMEIALQPNGFISGYMGTTLGFPGLELFFRNLDGSGELLR
QVDLRGKTIVNDSRLLSTVMAGTNIIQSFSFELSTDGEPFYRGTAVFGYFKAEALKDQLG
LDNGKTTQPWHQAKGITPDIRVDLLDKGGRHFNAPAGQPHYRLAGGQLNFIDSVEIVDNG
GTHGLGYLYAERTIDPSDWFFQFHFHQDPVMPGSLGVEAIIETMQTYAISKDLGAGFTNP
KFGQILSNIKWKYRGQINPLNKQMSMDVSITSVKEDAGKLVITGNASLSKDGLRIYEVSD
IAICIEEA