Protein Info for Shew_2583 in Shewanella loihica PV-4

Annotation: electron transfer flavoprotein, alpha subunit (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 PF01012: ETF" amino acids 3 to 167 (165 residues), 119.4 bits, see alignment E=1.7e-38 PF00766: ETF_alpha" amino acids 188 to 268 (81 residues), 121.7 bits, see alignment E=1e-39

Best Hits

Swiss-Prot: 65% identical to ETFA_PSEAE: Electron transfer flavoprotein subunit alpha (etfA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03522, electron transfer flavoprotein alpha subunit (inferred from 100% identity to slo:Shew_2583)

Predicted SEED Role

"Electron transfer flavoprotein, alpha subunit" in subsystem Acetyl-CoA fermentation to Butyrate

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QG51 at UniProt or InterPro

Protein Sequence (307 amino acids)

>Shew_2583 electron transfer flavoprotein, alpha subunit (RefSeq) (Shewanella loihica PV-4)
MAILVIAEHDNATLKLDTAKVVACAQAIGSEVDVLVAGHNCGAAADSAKQLAGVRQVLVA
DSGVYANAIAENLSQLIVSVASEYQHILAAASSVGKDVLPRVAALLDVAQLSEVVEVVSE
DTFVRPIYAGSAMATVQSLDNIKVMTVRASAFDAVAQDGSASVQTLDNEYSGDVEFVTQT
LSVSERPDLGAASVVVSGGRAMGSAENFAILEQLADKLGGALGASRAAVDAGYVPNDLQV
GQTGKIVAPDLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLEADLFEAV
PKLLELL