Protein Info for Shew_2569 in Shewanella loihica PV-4

Annotation: MerR family transcriptional regulator (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 133 PF13411: MerR_1" amino acids 11 to 76 (66 residues), 57.2 bits, see alignment E=2.1e-19 PF00376: MerR" amino acids 12 to 46 (35 residues), 39 bits, see alignment E=8.3e-14 PF09278: MerR-DNA-bind" amino acids 53 to 118 (66 residues), 55.5 bits, see alignment E=1.1e-18

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2569)

Predicted SEED Role

"Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family" in subsystem HMG CoA Synthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QG37 at UniProt or InterPro

Protein Sequence (133 amino acids)

>Shew_2569 MerR family transcriptional regulator (RefSeq) (Shewanella loihica PV-4)
MSDKHSPQTTYSISDLSKEFDITTRSIRFYEDQGLLKPKRRGQTRIYGLKDRVRLKLILR
GKRLGFSLAETRRLFELYDADKNSSTQLHTMLELVEEKKSALQQQMDDIKVVLMELNSAE
QQCRAALEQQERA