Protein Info for Shew_2522 in Shewanella loihica PV-4

Annotation: decaheme cytochrome c (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 720 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF22112: OmcA-like_N" amino acids 56 to 214 (159 residues), 246.8 bits, see alignment E=2.1e-77 TIGR03507: decaheme c-type cytochrome, OmcA/MtrC family" amino acids 62 to 718 (657 residues), 398.9 bits, see alignment E=2.3e-123 PF22113: Mtrc-MtrF_II-IV_dom" amino acids 221 to 338 (118 residues), 66.6 bits, see alignment E=4.2e-22 amino acids 550 to 716 (167 residues), 102.9 bits, see alignment E=3e-33

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2522)

Predicted SEED Role

"surface localized decaheme cytochrome c lipoprotein, OmcA"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFZ0 at UniProt or InterPro

Protein Sequence (720 amino acids)

>Shew_2522 decaheme cytochrome c (RefSeq) (Shewanella loihica PV-4)
MEGTMMDMKKKVNQWSLIALSCSALLLGCGSDGKDGKDGPDGVIGVSITDTPSVMAQFTQ
ASVEDGQVSVTFKLENANGVAVLGLTKDYDLRFGIAQLAQVTETIDGQSFDRGYQWQAYI
NSLRQPGSLPDDTSGLNPSPKYQANVEAASACEDCLTDNLDGSYTYKFQQNIANVTEPLA
ITYNGDNTHRVTLELKLPQATANAHHDWQPSSGSADGIQTRNVVRKETCLNCHQEESLAL
HGGRRISLENCASCHTATSGDPESGNSIEFTYLIHAIHKGQDRVTSTPEGIVPAPYKIVG
FGGSLHDYGKVMFPQKPAANCAACHKEGDGAPSDAALFKADNSSIACISCHTEKPSQNHS
STNCVACHNATDTYPGTGNAEKRHGDVLKAYSLAQAMGVSFSNIGLDGDGKLKFDLQVTD
SAGNPVASEFIELGTRVVVAWDVDKDYPAYTDASYSNRRFRLSQGTYDDVSKTFTIVASS
FDMPMDAAGKTFELWSAIEVCFNHGGYGVADVVMTACSDDTRSVAVKEAPYRFVWSGTGV
AEDGQVAMRRAIVDTSKCQTCHNQENHHYNNGYNCQTCHTSDKTTSGDDSYPGGRRPTSF
AFKAHEAEGHYLKYAGVQSGTVLKTDCLTCHTDDGITLGRASDRVWRYGDTTTGVDIWVS
SDAGACLSCHQKYLKDSGAAHIQANGGILDGMDADDVRARAAETCATCHTPTQLLGIHQE