Protein Info for Shew_2420 in Shewanella loihica PV-4

Annotation: peptidase M16 domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 925 PF00675: Peptidase_M16" amino acids 23 to 160 (138 residues), 108.1 bits, see alignment E=6e-35 PF05193: Peptidase_M16_C" amino acids 183 to 358 (176 residues), 107.6 bits, see alignment E=1.1e-34 amino acids 648 to 826 (179 residues), 46.6 bits, see alignment E=5.6e-16 PF16187: Peptidase_M16_M" amino acids 367 to 645 (279 residues), 292.4 bits, see alignment E=4.6e-91

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2420)

Predicted SEED Role

"Protease III precursor (EC 3.4.24.55)" (EC 3.4.24.55)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.24.55

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFN8 at UniProt or InterPro

Protein Sequence (925 amino acids)

>Shew_2420 peptidase M16 domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MPITKSPNDHRQYQYLQLDNGLRVLLVEDLQAQQAAASMAVNVGHFDDPASRPGMAHFLE
HMLFLGTEKYPKSGEYHAFINQHGGSNNAWTGTEQTNFFFSIDAEVFEESLDRFSQFFIA
PCFDLELVDRERHAIESEFSLKLKDDIRRTYQVQKETVNPAHPFSKFSVGNLKTLDGDEK
TLRQELLDFYQTHYSANLMTLCLVAPLPLDELLALAESYFVPIENRKLAKQYPNVAIYEA
AQLGQQINIVPLKEQRRVAITFPLPAIDRFYKRKPLTFISHLLGYEGKGSLLSHLKDQGL
AINLSAGGGVNGYNFKDYNISIQLTEKGLLQLDDVIQASFEYLKLIKTQGMQAWRYQERA
NLLKLAFKYQEQIKPLDLASHLSINMHHYEVSDLIYGDYRMDGLDVAQVTELLDLMSPDN
LRIQLISPDLDTEKQASWYHSPYQMKPIDAQRLKHWREPEIREALKLPEPNPFIIEDSIA
RDVKSDHPVPVVVCQETGYRIWHKKDDEFNVPKGHMYLSLDSHQAAATPKHAALTRLYVE
MLLDYLTEFTYPAEVAGLSYNIYPHQGGITLHLTGLTGKQEALLSLLINKARERNFTQDR
FKQIKKQILRNWFNQSRAKPISQLFTSLTVTLQKRSFEPQRMAEELEDITLDDLHNHVRA
FYEKIHLEGLVYGDWLTEEAQALGKRLDHILSLVSSPSGESERELIKLENVGTLMREVSV
NHQDSSIIVYYQSAQATPLKMALFSLLNHTMSSTFFHELRTKRQLGYMVGTGYLPLNRYP
GMIFYVQSPTAGPLKLLEAIDEFIADFNYAVMQITNDQWELTKQGLINQIMEHDPNLKTR
GQRYWSSIGNKDYDFNQRELVAEQIGELTRSDLIKFMMQKMRTKHGDRLILFTTGEQHRN
QEQLTSDNMITDLRSFKQRAAKFSY