Protein Info for Shew_2386 in Shewanella loihica PV-4

Annotation: hypothetical protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 509 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 108 to 129 (22 residues), see Phobius details amino acids 150 to 168 (19 residues), see Phobius details amino acids 174 to 200 (27 residues), see Phobius details amino acids 210 to 229 (20 residues), see Phobius details amino acids 235 to 254 (20 residues), see Phobius details amino acids 291 to 313 (23 residues), see Phobius details amino acids 319 to 337 (19 residues), see Phobius details amino acids 357 to 375 (19 residues), see Phobius details amino acids 395 to 418 (24 residues), see Phobius details amino acids 430 to 450 (21 residues), see Phobius details amino acids 457 to 476 (20 residues), see Phobius details amino acids 485 to 507 (23 residues), see Phobius details PF03606: DcuC" amino acids 18 to 504 (487 residues), 444.8 bits, see alignment E=1.6e-137

Best Hits

Swiss-Prot: 64% identical to YFCC_ECOLI: Putative basic amino acid antiporter YfcC (yfcC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to slo:Shew_2386)

Predicted SEED Role

"Putative S-transferase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFK4 at UniProt or InterPro

Protein Sequence (509 amino acids)

>Shew_2386 hypothetical protein (RefSeq) (Shewanella loihica PV-4)
MANQAPSPAVNPQKKIPLPDTLVIIFFVALAAMLLTYLVPVGSFETQEIHYLADGVEKQR
SVVDPNSFRFSLDEAGEHLKQPVALFEGGGGVGFFNFAFEGLTSGSKWGTAIGVIMFMLV
IGGAFGIVMETGTIDNGIIRLIDKTQGNERLFIPVLFILFSLGGAVFGMGEEAIAFAIII
CPLMIRLGFDGITTVMVTYVATQVGFASSWMNPFSVAIAQGIAGIPVLSGAGVRGVMWAG
FTLMGVIFTMRYGAKIQANPQSSLCYESDRYFREHHGANELQSRFNLGDSLVLLTILLTV
IWVIWGVVANAWFIPEIASQFFAMGIVVGMIAVIFRLNGMTLNRMATSFKQGAGTMLEPA
LLVGCASGILLLLGGGKPDEPSVLNTLLNSAGSLIGQLPAVASAWFMLLFQSVFNFFVTS
GSGQAALTMPLMAPLADIVGVSRQVAVLAFQLGDGFTNVLVPTSASLMATLGVCRVDWGI
WVKFIWRFMLALFLVSSLVVVAAHYLGFV