Protein Info for Shew_2286 in Shewanella loihica PV-4

Annotation: SSS family solute/sodium (Na+) symporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 519 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 45 to 65 (21 residues), see Phobius details amino acids 72 to 93 (22 residues), see Phobius details amino acids 124 to 144 (21 residues), see Phobius details amino acids 156 to 173 (18 residues), see Phobius details amino acids 181 to 202 (22 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 281 to 307 (27 residues), see Phobius details amino acids 329 to 350 (22 residues), see Phobius details amino acids 371 to 393 (23 residues), see Phobius details amino acids 403 to 425 (23 residues), see Phobius details amino acids 432 to 451 (20 residues), see Phobius details amino acids 457 to 478 (22 residues), see Phobius details amino acids 499 to 518 (20 residues), see Phobius details PF00474: SSF" amino acids 38 to 438 (401 residues), 229.8 bits, see alignment E=2.9e-72 TIGR00813: transporter, solute:sodium symporter (SSS) family" amino acids 38 to 437 (400 residues), 359.1 bits, see alignment E=1.8e-111

Best Hits

KEGG orthology group: K03307, solute:Na+ symporter, SSS family (inferred from 100% identity to slo:Shew_2286)

Predicted SEED Role

"Predicted sodium-dependent galactose transporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QFA4 at UniProt or InterPro

Protein Sequence (519 amino acids)

>Shew_2286 SSS family solute/sodium (Na+) symporter (RefSeq) (Shewanella loihica PV-4)
MLETLDIGILLVYALGLLGLALWISRQDKRHERDTKDYFLAGKALPWWAIGASLIASNIS
AEQIIGMSGSGYAIGLAIASYEWMAAITLILVGKYMLPIFIKNEIYTMPQYLEQRFDKRV
KTTLALFWLSVYILVNLTAVLWLGGLAIETVAGIDWLYGMVFLALFSLAYSLYGGLKAVA
YTDIIQVVLLIFGGLLLSYLALDRVADGQGVLAGFDRLSSALPEHFEMILSQSNPHYMSL
PGISVLVGGLWIMNISYWGFNQYIIQRALAAKSVAEAQKGIAFAAYLKLLMPLIVVLPGI
AAVLLYPGLESPDQAYPSMMALMPAGVKGLVFAALVAAIVSSLASMTNSISTIFTMDIYA
MLRPAKSEGHYVLVGRLSSLISLLIALVMAQPLLGEFEQAFQYIQEFTGVFTPGIVVIFL
TGMFWRRATSQGALAAALGSAIFSFGLRFYWPELPFMDRIGLVFLLCLALSVLVSLMGRS
LEEGASVALGGVSFKTGRAFNVSALGVVVILNFLYVTWW