Protein Info for Shew_2250 in Shewanella loihica PV-4

Annotation: phosphotransferase domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02811: PHP
  • amino acids 9 to 147 (139 residues), 43.5 bits, E=2.3e-15

Best Hits

Swiss-Prot: 56% identical to RNAAM_SALTY: 5'-3' exoribonuclease (trpH) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K07053, (no description) (inferred from 100% identity to slo:Shew_2250)

MetaCyc: 56% identical to RNase AM (Escherichia coli K-12 substr. MG1655)
RXN-16009 [EC: 3.1.3.97]; 3.1.13.- [EC: 3.1.3.97]; RXN-24047 [EC: 3.1.3.97]

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.97

Sequence Analysis Tools

See A3QF68 at UniProt or InterPro

Protein Sequence (286 amino acids)

>Shew_2250 phosphotransferase domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MTDETRLIDLHSHTTASDGQLTPSELVARALDNGVQMLAITDHDTLAGLKEAHSFNDSQA
EPLTLINGCEISTRWNNFDIHIVALNIDPEHQGLDTFLTQQRALREARAMEIGVRLEKAG
ISGAYEGAKALAEGAALSRGHYARWLADNGYATNAAAVFKKYLARGKTGYVPNNWSDMET
AIAIIHEAGGVAVLAHPSGYKLSAKWLKRLVREFKAAGGDAMEVVLGQQTLDDRNNLIAL
SRLNELHASLGSDFHFPGSWLELGRNMFQPQGVDWVWQMDNWMGNP