Protein Info for Shew_2248 in Shewanella loihica PV-4

Annotation: chromosome segregation and condensation protein ScpA (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 262 PF02616: SMC_ScpA" amino acids 49 to 260 (212 residues), 110.4 bits, see alignment E=7.2e-36

Best Hits

Swiss-Prot: 53% identical to SCPA_XYLFA: Segregation and condensation protein A (scpA) from Xylella fastidiosa (strain 9a5c)

KEGG orthology group: K05896, segregation and condensation protein A (inferred from 100% identity to slo:Shew_2248)

Predicted SEED Role

"Segregation and condensation protein A" in subsystem Two cell division clusters relating to chromosome partitioning

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QF66 at UniProt or InterPro

Protein Sequence (262 amino acids)

>Shew_2248 chromosome segregation and condensation protein ScpA (RefSeq) (Shewanella loihica PV-4)
MQGTQQSLPLAVVRGEPVKELPADLFIPPEALEVFLESFEGPLDLLLYLIRKQKLDVVEM
AIAPVTDQYLEYIELLQGARVELAADYLVMAATLAEIKSRLLLPRPELAEEDEADPRAQL
IRQLKAYEVIKDAQQRLDALPRLERDVFQAKVLPAPDIKPVLVPPSVSLVELAGAFAAVL
KRVEATEHHHVQREHLSTRERMTQILAMLEGKSYVPFEQLFDVSEGRAGVVVSFLALMEL
VKELLVDLIQAQPLSTIHVRAY