Protein Info for Shew_2053 in Shewanella loihica PV-4

Annotation: peptidyl-dipeptidase A (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 634 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF01401: Peptidase_M2" amino acids 61 to 634 (574 residues), 802.6 bits, see alignment E=1.2e-245

Best Hits

KEGG orthology group: K01283, peptidyl-dipeptidase A [EC: 3.4.15.1] (inferred from 100% identity to slo:Shew_2053)

Predicted SEED Role

"Peptidyl-dipeptidase A precursor (EC 3.4.15.1)" (EC 3.4.15.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.15.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QEM1 at UniProt or InterPro

Protein Sequence (634 amino acids)

>Shew_2053 peptidyl-dipeptidase A (RefSeq) (Shewanella loihica PV-4)
MKPICAKLTPVAVVIALSLGIGGCNDDNNANTESKATAESKAQQAAGQDGLKQQTSEQDK
LAEAKQFISNAESQLADLSIEQNRAEWIYSNFITEDTATLAASVGERQTALSVQLATQAA
NYSQLPLDEVNTRKLNILRSALVLPAPLDPKKNAELANISAELNGLYGKGKYCLADGRCL
TQPELSGIMASSRDPKELEEIWKGWREIAKPMRPLFEREVELANEGAKDLGYANLSELWR
SQYDMQPDAFSAELDRLWGQVEPLYESLHCYVRGELNEKYGDEVAPNKGPIPAHLLGNMW
AQQWGNVYDMVAPQDADPGYDVTELLAKQGYDEHQMVKQAEGFFTSLGFDALPETFWSRS
LFLQPKDRDVVCHASAWDLNNLDDIRIKMCIQKTAEDFTVIHHELGHNFYQRAYKEQPFI
FKNSANDGFHEAIGDTVALSITPNYLKQIGLLQEVPDASKDIGLLLRQALDKVAFLPFGL
MIDQWRWKVFSGEITPAQYNQAWWELREKYQGVKAPIARSEADFDPGAKYHVPGNVPYTR
YFLAHILQFQFHKALCDIAGDKGPVHRCSIYGNKDAGAKLNAMLEMGQSKPWPEALEVVT
GSQNMDASAVLDYFAPLKVWLDKQNKQANRQCGW