Protein Info for Shew_1983 in Shewanella loihica PV-4

Annotation: response regulator receiver modulated metal dependent phosphohydrolase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 523 PF00072: Response_reg" amino acids 29 to 145 (117 residues), 32.3 bits, see alignment E=2e-11 PF11849: DUF3369" amino acids 149 to 324 (176 residues), 155.7 bits, see alignment E=2.7e-49 PF13487: HD_5" amino acids 336 to 501 (166 residues), 131.9 bits, see alignment E=4.2e-42 PF01966: HD" amino acids 347 to 469 (123 residues), 60.9 bits, see alignment E=2.9e-20

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1983)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QEF1 at UniProt or InterPro

Protein Sequence (523 amino acids)

>Shew_1983 response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) (Shewanella loihica PV-4)
MLIDMAKKSPLFSGKKKAAETETGPAWRILIVDDEPDVHTVTKLALSRFKLDNRGIEFIN
AYSGEEAKRVLQDEKDVAMAFIDVVMESDHAGLELVKWIREEHNDRSIRLILRTGQPGQA
PEEDVIVNYDINDYKAKAELDSRKLITSVYSALRSYRDIMEIEAAKQTQIRYREGLERVV
KATSGLFELRTLYHFADGLLTQVANLLNLNNETLLLTCNAIDAMSKDLSTDKLHILAGTG
QFASHHEQAIPEPIEKLLKRALQEQTCLYEDNLFVGYFPAKSGWINLLYMDNIHAIGDLD
KKLIDIFAINVGVAFENLLLNKELEDTQSELIFRLGDVVESRSKEAANHVKRMAEYCYIL
AKLAGLDDQQADLIKHASPMHDIGKIATPDAVLLKPGKLNDEEWQIMRQHPAIGHQILGN
SERPILNAAAIIALQHHEKYDGSGYPDGLKGDEIHIFARIVAIADVFDALSHERCYKPAW
PLDEVIAEIAKGAGSHFDPDLTSLFIDNIEHFNKVRLALTDSN