Protein Info for Shew_1874 in Shewanella loihica PV-4

Annotation: major facilitator transporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 524 transmembrane" amino acids 27 to 47 (21 residues), see Phobius details amino acids 67 to 88 (22 residues), see Phobius details amino acids 100 to 116 (17 residues), see Phobius details amino acids 122 to 140 (19 residues), see Phobius details amino acids 160 to 182 (23 residues), see Phobius details amino acids 202 to 220 (19 residues), see Phobius details amino acids 256 to 273 (18 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 331 to 352 (22 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details amino acids 406 to 423 (18 residues), see Phobius details amino acids 429 to 451 (23 residues), see Phobius details amino acids 462 to 489 (28 residues), see Phobius details amino acids 495 to 515 (21 residues), see Phobius details PF07690: MFS_1" amino acids 34 to 478 (445 residues), 80.4 bits, see alignment E=1.2e-26 PF13347: MFS_2" amino acids 72 to 269 (198 residues), 32.6 bits, see alignment E=3.3e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1874)

Predicted SEED Role

"Predicted maltose transporter MalT" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QE42 at UniProt or InterPro

Protein Sequence (524 amino acids)

>Shew_1874 major facilitator transporter (RefSeq) (Shewanella loihica PV-4)
MNNKEKHRMSQNTLPAQGTTTVKPALSFWQIFNMCFGFLGIQFGFALQNANVSRIFQTLG
AAIDDIPILWIAAPLTGLLVQPIIGYMSDNTWGRLGRRRPYFLIGAIFTTLAIFIMPHSP
VLWVAAGMLWIMDASINIAMEPFRAFVGDNLPTKQRPLGYAMQSFFIGVGAVVASALPYL
LTNYFDVANTAPEGEIADSVRYAFYFGGAVLLLAVSWTVFTTKEYSPEELARFEQENGEQ
VTLHHDRSWLAYQKGAMLWSLVGAILTAVIFLQSLDKQLYLLALGIFAFGPLQWFCANTL
KHIKGEERHQQGMVFSVVDALFHMPKAMRQLAVVQFFSWFALFSMWIYTTAAVTDHHYGT
QDVLSKAYNDGADWVGMLFASYNGFAAVAAIFIPLLAMAVGLKVTHLINLCCGGIGLISF
YFIQDPNLLWLPMIGVGIAWASILSIPYALLSNALPAAKMGVYMGIFNFFIVIPQLLAAS
VLGVLLNAFFDGKPIFALILGGSFMILAGISVLFVSSEASKAER