Protein Info for Shew_1849 in Shewanella loihica PV-4

Annotation: NlpB/DapX family lipoprotein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details PF06804: Lipoprotein_18" amino acids 31 to 366 (336 residues), 356.5 bits, see alignment E=6.1e-111

Best Hits

Swiss-Prot: 73% identical to BAMC_SHESH: Outer membrane protein assembly factor BamC (bamC) from Shewanella sediminis (strain HAW-EB3)

KEGG orthology group: K07287, lipoprotein-34 (inferred from 100% identity to slo:Shew_1849)

Predicted SEED Role

"Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QE17 at UniProt or InterPro

Protein Sequence (373 amino acids)

>Shew_1849 NlpB/DapX family lipoprotein (RefSeq) (Shewanella loihica PV-4)
MLKQVTPILLVAAVTACSTPIDRRQANGDDEYANVTSQPKLVIPAGLNQPKYNTEFDIPE
VGSKVDKTLVGKKLDIRPPLQVLPMAEGTHVEESSDSIKIVVESIDNDIDLRSELFSILD
EYFSQHEIKILKEDRDTGVIETDWIENQEVIDSSLWGSDEVYSVRQRYRFSVNVRPHGRS
GNLAIELIDHEESFDGKAQDILLTGEDKRRYTVDMLNNTIAYMSVKRAKAIKAKRLRESL
GIDVALVKAPAVAENETPEQSFWLADASYSRTWDRLRIVLPELGFEIVDMDSNKGLYYIN
VSDDSGFWSSLWSDKKLPMEEGSYRLQIEQDKGDTSKTRIYLKDKEDSPVSNEVVEAVYD
GMAELMSEDRKVR