Protein Info for Shew_1823 in Shewanella loihica PV-4
Annotation: putative AcnD-accessory protein PrpF (RefSeq)
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 76% identical to PRPF_SHEON: 2-methyl-aconitate isomerase (prpF) from Shewanella oneidensis (strain MR-1)
KEGG orthology group: K09788, hypothetical protein (inferred from 100% identity to slo:Shew_1823)Predicted SEED Role
No annotation
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
See A3QDZ1 at UniProt or InterPro
Protein Sequence (389 amino acids)
>Shew_1823 putative AcnD-accessory protein PrpF (RefSeq) (Shewanella loihica PV-4) MKQMKIPATYMRGGTSKGVFFALKDLPLNAQQPGPARDALLLRVIGSPDPYGKQTDGMGG ATSSTSKTVILDKSQRDDHDVDYLFGQVAIDKPFVDWSGNCGNLTAAVGAFAITQGLVDS AKIPDNGIAVVKIWQANINKTIIAHVPMVDGEVQELGDFELDGVTFPAAEVLVEFVDPAD GEGDMFPTGNLVDKLEVPGEPVFDATFINAGIPTIFLKAEQLGYEGTELQEAINGDAAAL ERFETIRAHGALQMGLIQSLDEAAGRQHTPKIAFVAPAKAYTSSSGKQIAAEEIDLHVRA LSMGKLHHAMMGTAAVAIGTAASIPGTLVNQAAGGQARESVRFGHPSGTLKVGAKASEQE GRWQVEKVSMSRSARVLMQGWVCVPESLG