Protein Info for Shew_1802 in Shewanella loihica PV-4

Annotation: carboxy-terminal protease (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 681 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF17804: TSP_NTD" amino acids 50 to 232 (183 residues), 211.3 bits, see alignment E=3.1e-66 TIGR00225: C-terminal processing peptidase" amino acids 196 to 554 (359 residues), 362.2 bits, see alignment E=1.2e-112 PF00595: PDZ" amino acids 238 to 319 (82 residues), 37.7 bits, see alignment E=4.6e-13 PF03572: Peptidase_S41" amino acids 363 to 532 (170 residues), 163.6 bits, see alignment E=6.3e-52 PF11818: DUF3340" amino acids 538 to 670 (133 residues), 130.2 bits, see alignment E=1.6e-41

Best Hits

KEGG orthology group: K03797, carboxyl-terminal processing protease [EC: 3.4.21.102] (inferred from 100% identity to slo:Shew_1802)

Predicted SEED Role

"Tail-specific protease precursor (EC 3.4.21.102)" (EC 3.4.21.102)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.102

Use Curated BLAST to search for 3.4.21.102

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDX0 at UniProt or InterPro

Protein Sequence (681 amino acids)

>Shew_1802 carboxy-terminal protease (RefSeq) (Shewanella loihica PV-4)
MRKLTLAASIASIFVGFSAWALTPSIPSSELPSLTQEPQHKVASKRVTGLFTRAHYHRFD
LDDAFSEQVFDRYLKQLDYRRNVLLQSDIDSFKPYATQFDDMLKSGDLTAAYKMFDLVQQ
RRYDRFAYALSLLDKEMDFNVPGDSYQYDRDDAAWPKDEAELNELWRQRVKYDALNLKLT
GKNWDEIVKVLDKRYNNAIKRLSQTKSEDVFQGVMNAFSRSVEPHTSYLSPRNAERFQME
MNLSLEGIGAVLQMDDDYTVIKSLVAGGPAANSEKLAPEDRIVGVGQEGKEIVDVIGWRL
DDVVELIKGPKGSKVVLQILPKKGGSSAKPIDVTIVRDKIRLEDRAATSEVIEPETGDYA
GRKVGVIKIPGFYMNLSQDVTKELVKLKDAKVEGVVIDLRGNGGGALTEATLLTGLFIEQ
GPVVQIRDANGKVSQNRDNDGRVTYSGPLTVMVDRYSASASEIFAAALQDYDRALIVGES
TFGKGTVQQHKSLGRIYDMYDKPIGHVQYTIAKFYRINGGSTQLKGVTPDIPFPSALEPG
EYGEAEEANALPWDKVPVAQYGTLGDITPELVTNLDSRHQQRIKKDVEFGYIDQDIAEFK
KSHKETSVSLVEKERVAEREANDEKQLARLNERRAVDGLEALKSLDDAEEDVKAPDAFLD
ETVYITLDLVDMERVAKNQAK