Protein Info for Shew_1787 in Shewanella loihica PV-4

Annotation: putative chaperone (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF00012: HSP70" amino acids 130 to 238 (109 residues), 31.7 bits, see alignment E=5.2e-12

Best Hits

Swiss-Prot: 50% identical to YEGD_ECOLI: Uncharacterized chaperone protein YegD (yegD) from Escherichia coli (strain K12)

KEGG orthology group: K04046, hypothetical chaperone protein (inferred from 100% identity to slo:Shew_1787)

Predicted SEED Role

"Putative heat shock protein YegD" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDV5 at UniProt or InterPro

Protein Sequence (461 amino acids)

>Shew_1787 putative chaperone (RefSeq) (Shewanella loihica PV-4)
MFVGFDYGSANCAVGIMEGERVQLLPLAGDSHYLVSTLYAFDRELIAEAVYQQLAGELKA
DYAKLRSAQLSRARHARQALDLDGDEQAVFVGEQAVAHYLEMPEEGFYVRSPKSFLGATG
LRADQIALFEDIVTLMMMHIKSLADKQLGAKGSATHAVIGRPVNFQGIGGEESNRQAEAI
LALAAKRAGFIEVSFLFEPLAAGMDFEASLTQDKTVLVVDVGGGTTDCSVVKMGPSHIAK
ADRSEDFLGHSGQRIGGNDLDIALAMKAFMPHLGLGSQMVNGLPVPSQPFWNAVAVNDIS
AQRDFASLTSRKMIEELIKDAERSDLLSRLLKVQRDQLGYRLVRSAEGAKIALSDNAATQ
SSLDYVDAALVAEVDQQGFVDAIAQPVGLIQSLMAEAMAKATDKATDKAQADIIYVTGGT
AKSPAIYQKIAQMYPETEIVVGDHFGSVTAGLTRWAQKVFG