Protein Info for Shew_1783 in Shewanella loihica PV-4

Annotation: secretion protein HlyD family protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 352 transmembrane" amino acids 7 to 28 (22 residues), see Phobius details PF16576: HlyD_D23" amino acids 41 to 278 (238 residues), 46.4 bits, see alignment E=5.9e-16 PF13533: Biotin_lipoyl_2" amino acids 45 to 90 (46 residues), 50.1 bits, see alignment 3.6e-17 PF13437: HlyD_3" amino acids 200 to 278 (79 residues), 24.6 bits, see alignment E=6.8e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1783)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDV1 at UniProt or InterPro

Protein Sequence (352 amino acids)

>Shew_1783 secretion protein HlyD family protein (RefSeq) (Shewanella loihica PV-4)
MTPDQQFARLVKFASIGFILLFGYFLVADLKMPLTTQAMATRTITQVAPQVSGRVVSVQV
ANNQKVQQGDLLFSLDATPFLLAQEQAELALEQARQDNAELDAAIAAATAEVNAKEIAYA
LKQREAKRIQSLYANQSVSQQMIDQAQTEVKASRSQLLAAKAQLAKVQTLRGLPGEDNLK
LRQAKNRLSQATLALSYTQIRAEHDGVVTNVQLASGNMVNQSTPVMALLLDNVDVIADFR
EKNLRHIAPGATALVAFDGRPGELFQASVSSVDAGVSQAQFDANGRLATPTESNRWVRDA
QRFRLHLELAPDVAITLPAGAKATVQLQPSNVIYELFAKVQIKFISLLHYIY