Protein Info for Shew_1590 in Shewanella loihica PV-4

Annotation: 2OG-Fe(II) oxygenase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 279 PF14226: DIOX_N" amino acids 10 to 94 (85 residues), 41.2 bits, see alignment E=2.4e-14 PF03171: 2OG-FeII_Oxy" amino acids 150 to 253 (104 residues), 66.6 bits, see alignment E=2.2e-22

Best Hits

KEGG orthology group: K04126, isopenicillin-N synthase [EC: 1.21.3.1] (inferred from 100% identity to slo:Shew_1590)

Predicted SEED Role

"Isopenicillin N synthase"

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.21.3.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QDA9 at UniProt or InterPro

Protein Sequence (279 amino acids)

>Shew_1590 2OG-Fe(II) oxygenase (RefSeq) (Shewanella loihica PV-4)
MKLETIDYRAQDSAQRFVESLRETGFGVLSNHPIDKALVDTIYEEWQAFFNSDEKHDYLF
KPETHDGFFPADVSETAKGHTVKDIKEYYHVYPWGRIPDSLRENILRYYQEANALAEELL
GWVEAHTPAEVAVNYSIALPKMIENSHKTLLRILHYPPMSGDEELGAIRAAAHEDINLLT
VLPAANEPGLQVKAKSGEWLDVPSDFGNLIINIGDMLQEASGGYFPSTTHRVVNPEGADK
TRSRISLPLFLHPKPEVVLSERYTADSYLMERLRELGVI