Protein Info for Shew_1451 in Shewanella loihica PV-4

Annotation: ABC transporter-related protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 609 transmembrane" amino acids 39 to 60 (22 residues), see Phobius details amino acids 83 to 108 (26 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details amino acids 268 to 289 (22 residues), see Phobius details amino acids 295 to 313 (19 residues), see Phobius details PF00664: ABC_membrane" amino acids 44 to 309 (266 residues), 68.1 bits, see alignment E=1e-22 PF00005: ABC_tran" amino acids 378 to 531 (154 residues), 122.3 bits, see alignment E=2.3e-39

Best Hits

Swiss-Prot: 58% identical to Y1051_HAEIN: Uncharacterized ABC transporter ATP-binding protein HI_1051 (HI_1051) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K06147, ATP-binding cassette, subfamily B, bacterial (inferred from 100% identity to slo:Shew_1451)

Predicted SEED Role

"Lipid A export ATP-binding/permease protein MsbA" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCX0 at UniProt or InterPro

Protein Sequence (609 amino acids)

>Shew_1451 ABC transporter-related protein (RefSeq) (Shewanella loihica PV-4)
MFKRFESWVSALPDQEAVQPPRGIYRFCRHYTRGFELPLALMSILTALLAILEVSLFAFM
GDLVDLLASHSPETLFAEQGDKLLLMAVLVLVVIPVLVLLHALVIYQGLLGNYPMSIRWL
AHRYLLKQSIAFYQNDFAGRIATKVMQTSLAVRETVTKLLDVLVYILVYFLSMLVIIADA
DLRLMLPMLVWLMIYVGLQFYYLPKLKQVSTEQADARSTMTGRIVDSYTNIATVKLFSHT
QKEAQYAKESMTGFLDTVYRQMRLVTGINVSVQVINYLLAFSVAAVSIWLWRDNAITIGA
IAVAVSLSLRLNGMSQWIMWEISSLFENIGTVADGMNTLSRPTSVQDSDNASQLTVSKGE
IAFNRVSFHYGEASGVIEDLDLKIKPGEKVGLVGRSGAGKSTLVNLLMRFHDVEQGSITI
DGQNIREVEQDSLRANIGMVTQDTSLLHRSIRDNIRYGKPDASEEELENAIRQAQAYEFI
QGLSDPEGNHGLDAQVGERGVKLSGGQRQRIAIARVLLKNAPILLLDEATSALDSEIEAA
IQESLYQLMEGKTVIAIAHRLSTIAAMDRLIVLDQGKIVEQGTHQELIKQGGIYAQLWAH
QTGGFLGIE