Protein Info for Shew_1450 in Shewanella loihica PV-4

Annotation: putative cytochrome P460 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 166 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF16694: Cytochrome_P460" amino acids 35 to 158 (124 residues), 119.7 bits, see alignment E=5.4e-39

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1450)

MetaCyc: 49% identical to cytochrome P460 monomer (Methylococcus capsulatus)
HAONITRO-RXN [EC: 1.7.2.6]

Predicted SEED Role

"putative cytochrome P460"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.7.2.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCW9 at UniProt or InterPro

Protein Sequence (166 amino acids)

>Shew_1450 putative cytochrome P460 (RefSeq) (Shewanella loihica PV-4)
MKRSLFLLLTAISLISSVSYAEDSTPLPSHQIAYPQGWQTWSSIAVSHRTDNNTVRAILG
NEIAVNAARSGNHMPWPDGAIFAKVVWKAGELTHWPQAIGPKAFVHAEFMFKDSVKYADT
YGWGWARWVGEEQTPFEGGMQVCISCHTPVKDNDWVFTEPAWFPNK