Protein Info for Shew_1441 in Shewanella loihica PV-4

Annotation: major facilitator transporter (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 46 to 66 (21 residues), see Phobius details amino acids 78 to 95 (18 residues), see Phobius details amino acids 102 to 123 (22 residues), see Phobius details amino acids 135 to 154 (20 residues), see Phobius details amino acids 164 to 186 (23 residues), see Phobius details amino acids 222 to 241 (20 residues), see Phobius details amino acids 253 to 271 (19 residues), see Phobius details amino acids 283 to 301 (19 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 342 to 361 (20 residues), see Phobius details amino acids 367 to 390 (24 residues), see Phobius details PF07690: MFS_1" amino acids 15 to 260 (246 residues), 100.2 bits, see alignment E=1.2e-32 amino acids 222 to 398 (177 residues), 52.4 bits, see alignment E=4.2e-18 PF00083: Sugar_tr" amino acids 46 to 183 (138 residues), 23.3 bits, see alignment E=2.8e-09

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1441)

Predicted SEED Role

"Major facilitator superfamily precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCW0 at UniProt or InterPro

Protein Sequence (405 amino acids)

>Shew_1441 major facilitator transporter (RefSeq) (Shewanella loihica PV-4)
MTASRPLQLRLIWGLSLASVVIYINLYMVQGMLPLIATSFSVSPAHATLLLSVTSFSMAF
ALLFYATLSDKLGRRKPLLWSLALLVVADLMLIWVQDFSALVAVRLFQGILLAAVPAIAM
AYFKDLLDTSVLLKAGAIYIGANSLGGIAGRLLGGLMTEYLTWVEAMGLVSVLTLAGVVG
VLLLLPRLDRVRIRRRQHKSGFGLADLKGFGLHLGDATLVKLYLLGALAFMVMVNQFSYI
QLHLMQAPFGWGKFQVTLIFLCYLSGTYASFRSAKWVTRLGRQPLFILSAVMMCVGSLVT
LGDTSSAIVIGFLLSSFGFFTFHSVCNAWVAQRAQQHRAKATALYLCSYYLGAALGGPFL
LPFWQHWGWSGVVAGSLTLLSGVILLVVMLQRNHRPHTPLLDAAG