Protein Info for Shew_1417 in Shewanella loihica PV-4

Annotation: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 347 transmembrane" amino acids 6 to 22 (17 residues), see Phobius details amino acids 43 to 64 (22 residues), see Phobius details amino acids 70 to 86 (17 residues), see Phobius details amino acids 98 to 118 (21 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details amino acids 157 to 175 (19 residues), see Phobius details amino acids 181 to 198 (18 residues), see Phobius details amino acids 210 to 232 (23 residues), see Phobius details amino acids 238 to 260 (23 residues), see Phobius details amino acids 292 to 312 (21 residues), see Phobius details amino acids 318 to 341 (24 residues), see Phobius details TIGR02380: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase" amino acids 6 to 346 (341 residues), 390.4 bits, see alignment E=3.9e-121 PF00953: Glycos_transf_4" amino acids 73 to 230 (158 residues), 118 bits, see alignment E=2.1e-38

Best Hits

Swiss-Prot: 43% identical to WECA_HAEIN: Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase (wecA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02851, undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase [EC: 2.7.8.-] (inferred from 100% identity to slo:Shew_1417)

Predicted SEED Role

"Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase (EC 2.7.8.-)" in subsystem Methicillin resistance in Staphylococci or Teichoic and lipoteichoic acids biosynthesis (EC 2.7.8.-)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.8.-

Use Curated BLAST to search for 2.7.8.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCT7 at UniProt or InterPro

Protein Sequence (347 amino acids)

>Shew_1417 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase (RefSeq) (Shewanella loihica PV-4)
MEYFIPFVTVFCLTCVAIKLFHPIAEKVGLVDLPNERKTHVGAIPLIGGVAIYCSVLLVS
SIVFEQNQVFNLYLISAALILFLGVLDDKYDLSVRVRIVAQVITASILVFGAGFYLTSLG
HITYFFELKLGYVGVFVTILAVIGAINAFNMVDGIDGLAGMLSLVTFTSLALLFYTAGNH
WFILPLLFIGAIIGYLIFNLRWPFETVQKIFMGDAGSMLIGLTVVWLLVLGVEADARVFA
PVTALYLIGIPLMDMAAIMYRRVKKGMSPFKPDRDHLHHIFERAGYSRKQTLVRISLASI
VLAALGVSGEWMLVPEWIMFLGFVAIFVAYNWALSHIWQILTWLRKA