Protein Info for Shew_1292 in Shewanella loihica PV-4

Annotation: tetratricopeptide TPR_4 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 207 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details PF09976: TPR_21" amino acids 15 to 205 (191 residues), 199.9 bits, see alignment E=5.5e-63

Best Hits

Swiss-Prot: 36% identical to YFGM_ECOLI: UPF0070 protein YfgM (yfgM) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to slo:Shew_1292)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QCG4 at UniProt or InterPro

Protein Sequence (207 amino acids)

>Shew_1292 tetratricopeptide TPR_4 (RefSeq) (Shewanella loihica PV-4)
MEIYSTEEQQVDAIKQFWKDYGNSIVIGAVVGLGGLYSWNYYSDYKVAQAEEASEAFQTI
SNSVKADSSMLAAAESFAKDHDGQQGYQALLQLIVAKAAVEAGELDKAEQALKQILVSKP
EEGLVAVATLRLARVQAEQGQLATALATLEQLNTPSFAVQRDELKGDFLVRQGDADKAKS
AYQSALDNGGATSSPALQMKLDNLNKA