Protein Info for Shew_1196 in Shewanella loihica PV-4

Annotation: recombination and repair protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 PF13175: AAA_15" amino acids 1 to 388 (388 residues), 33 bits, see alignment E=8.3e-12 TIGR00634: DNA repair protein RecN" amino acids 1 to 552 (552 residues), 575.8 bits, see alignment E=6.5e-177 PF02463: SMC_N" amino acids 2 to 509 (508 residues), 60.8 bits, see alignment E=2.1e-20 PF13476: AAA_23" amino acids 4 to 214 (211 residues), 55 bits, see alignment E=2.7e-18

Best Hits

Swiss-Prot: 57% identical to RECN_ECOLI: DNA repair protein RecN (recN) from Escherichia coli (strain K12)

KEGG orthology group: K03631, DNA repair protein RecN (Recombination protein N) (inferred from 100% identity to slo:Shew_1196)

Predicted SEED Role

"DNA repair protein RecN" in subsystem DNA-replication or DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QC68 at UniProt or InterPro

Protein Sequence (553 amino acids)

>Shew_1196 recombination and repair protein (RefSeq) (Shewanella loihica PV-4)
MLCQLSINNFAIVRFLELDFKSGMTSITGETGAGKSIAIDALGLCLGNRADANTVRPGAS
KAEVSARFALNDIPLAKRWLEDNDLELDDECILRRTIGSDGRSRAYINGNPVPLNQMRAL
GQQLIGIHGQHAHHAMLKSEHQLTLLDSYANHKMLLEACSASYQRFKLIQKELSQLQQSQ
HERIARKQLLQYQVEELDEFALGEEEFDEIEAEHKKLANGTALIQACQRTLYLLQDNEEG
AIESLLNMSLDQAQELEGYDPELKGVGNMLNDALIQVQESSSELQRYLDKLELDPEHFAA
LEQRLSKIMMLARKHHVNAKDLYQHHQALSQELSELDSDEEKLDEIAQQLESCRESFIAH
AQKLSQSRQRYAKELDKQVTRSIHELSMPKGKFIIDVQFNPEMMSPNGCDTVEFQVTTNP
GQPLQPIAKVASGGELSRIGLGIQVITAKKVATPTLIFDEVDVGISGPTAAVVGKMLRAL
GESTQVLCVTHLPQVAGNGHQHMFVNKQSKAGQTETSMVPLDKGQRIEELARLLGGDVIT
NNTLANAKELLQG