Protein Info for Shew_1108 in Shewanella loihica PV-4

Annotation: methylation site containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 163 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07963: N_methyl" amino acids 2 to 27 (26 residues), 34.3 bits, see alignment 1.2e-12 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 6 to 28 (23 residues), 30 bits, see alignment 1.6e-11 PF12019: GspH" amino acids 44 to 152 (109 residues), 63.2 bits, see alignment E=2.9e-21

Best Hits

KEGG orthology group: K08085, type IV fimbrial biogenesis protein FimU (inferred from 100% identity to slo:Shew_1108)

Predicted SEED Role

"type 4 fimbrial biogenesis protein FimU" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBY1 at UniProt or InterPro

Protein Sequence (163 amino acids)

>Shew_1108 methylation site containing protein (RefSeq) (Shewanella loihica PV-4)
MMKNKNGFTLVELMVTIVVAGIILTIGLPSLISAYESVRVNRSIERIHNLMSFARNQAIS
YGATVNVCPFASATSCGTGTNWKGGIRVYLTDAGGTDKELRAIDGFDTNDSVKGSGPLIT
FSADGLSSSGSIIYCPNGKASESQSVTISSSGLISYGADGNSC