Protein Info for Shew_1090 in Shewanella loihica PV-4

Annotation: OmpA/MotB domain-containing protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 367 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF13505: OMP_b-brl" amino acids 9 to 194 (186 residues), 75.8 bits, see alignment E=7.2e-25 PF01389: OmpA_membrane" amino acids 27 to 197 (171 residues), 91.3 bits, see alignment E=1e-29 PF00691: OmpA" amino acids 255 to 351 (97 residues), 67.8 bits, see alignment E=1.4e-22

Best Hits

KEGG orthology group: K03286, OmpA-OmpF porin, OOP family (inferred from 100% identity to slo:Shew_1090)

Predicted SEED Role

"Outer membrane protein A precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBW3 at UniProt or InterPro

Protein Sequence (367 amino acids)

>Shew_1090 OmpA/MotB domain-containing protein (RefSeq) (Shewanella loihica PV-4)
MMNNTLKAILLTSMLPFAANAAQELTPWYVGGGLGVNNYEPNCDQKTMKQCGEDDPYAWD
VFGGYLFNDYFGVELGYRDLGRAEWVDYANKLNDVGARGMTLGLVGFWPFADRWSLSAEA
GAMNYLLSNNKQWGSEYYSDSGVAPYFGAGIGYNFTDNLKLQAKYRRYENLDEDKWNTLD
MESNYWGLELSYRFGRAAPAAVAAPVVVAPKDSDNDGVTDDKDQCANTPSNHKVDANGCT
VYREVTEKHELGSIRFANNSAVVNSASYGQIEKLANYMNQNPRATVLIGGHASNVGNPDY
NMDLSERRANAVAELLVSKYGISQDRVSAKGYGITQPLIEGKSAEANKANRRIEAHVTGV
RKEPVLK