Protein Info for Shew_1056 in Shewanella loihica PV-4

Annotation: DNA repair protein RecO (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 PF11967: RecO_N" amino acids 3 to 72 (70 residues), 52.8 bits, see alignment E=3.4e-18 TIGR00613: DNA repair protein RecO" amino acids 3 to 219 (217 residues), 71.5 bits, see alignment E=3.5e-24 PF02565: RecO_C" amino acids 82 to 217 (136 residues), 41.7 bits, see alignment E=1e-14

Best Hits

Swiss-Prot: 43% identical to RECO_PSEU5: DNA repair protein RecO (recO) from Pseudomonas stutzeri (strain A1501)

KEGG orthology group: K03584, DNA repair protein RecO (recombination protein O) (inferred from 100% identity to slo:Shew_1056)

Predicted SEED Role

"DNA recombination and repair protein RecO" in subsystem DNA repair, bacterial RecFOR pathway

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBS9 at UniProt or InterPro

Protein Sequence (231 amino acids)

>Shew_1056 DNA repair protein RecO (RefSeq) (Shewanella loihica PV-4)
MHRGYVLHTRPYRESSVLVNLLVDGLGRVDAVARLGSGKTSIKSILQPFQPLLFQLSGRS
SLKSLYQVEAASPAVPLSGNDSFAGFYLNELLVRCLSVEHGAEQFFFTYHKTLMAMAAAF
SEAQLRQFELSLLKELGVMPSLNLDIEGSPIETDFYYRLLSEEGFSTALGPKPNHFSGEM
LRALEEDRLTEADFKQAKLLMRQLLSPLLGDKPLKSRALFLKGNRPSSYSK