Protein Info for Shew_1033 in Shewanella loihica PV-4

Annotation: putative radical SAM protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 330 TIGR01212: radical SAM protein, TIGR01212 family" amino acids 26 to 319 (294 residues), 375.1 bits, see alignment E=1.1e-116 PF04055: Radical_SAM" amino acids 62 to 219 (158 residues), 70.8 bits, see alignment E=1.6e-23 PF16199: Radical_SAM_C" amino acids 228 to 311 (84 residues), 76.2 bits, see alignment E=1.8e-25

Best Hits

Swiss-Prot: 55% identical to YHCC_ECOLI: Protein YhcC (yhcC) from Escherichia coli (strain K12)

KEGG orthology group: K07139, (no description) (inferred from 100% identity to slo:Shew_1033)

Predicted SEED Role

"COG1242: Predicted Fe-S oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBQ6 at UniProt or InterPro

Protein Sequence (330 amino acids)

>Shew_1033 putative radical SAM protein (RefSeq) (Shewanella loihica PV-4)
MAPSSQLQSPPFYRSREYPVGLDSHVNTFGLHCKRQYGQRLKKLTLDAKFTCPNRDGTLG
RGGCTFCNVASFSHEHGSIDSIAVQLANGRERAQGKSSKFIAYFQAYTSTYDEYQLLKQR
YDEAVADSDIVGLCVGTRPDCVSDEVIALLAGYQARGLEVWLELGLQSANLETLKRINRG
HGFEEYRDTVIRARKAGLKVCTHLILGLPGESHEDFLASHRAVLDAGVDGLKIHPLHIVE
GSTMAKAWRAGRMSLLTQEAYAESVGELIRLTPKEVIFHRVTAYAKKPMLLAPDWCAYRW
EGLVAIVKNLERLGGQGHYLTDSAGDQLSV