Protein Info for Shew_0952 in Shewanella loihica PV-4

Annotation: peptidase M24 (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 595 transmembrane" amino acids 183 to 194 (12 residues), see Phobius details PF01321: Creatinase_N" amino acids 8 to 137 (130 residues), 55 bits, see alignment E=2.6e-18 PF16189: Creatinase_N_2" amino acids 149 to 307 (159 residues), 120.5 bits, see alignment E=1.5e-38 PF00557: Peptidase_M24" amino acids 313 to 524 (212 residues), 173.7 bits, see alignment E=9.1e-55 PF16188: Peptidase_M24_C" amino acids 535 to 595 (61 residues), 85 bits, see alignment E=5.4e-28

Best Hits

KEGG orthology group: K01262, Xaa-Pro aminopeptidase [EC: 3.4.11.9] (inferred from 100% identity to slo:Shew_0952)

Predicted SEED Role

"Xaa-Pro aminopeptidase (EC 3.4.11.9)" (EC 3.4.11.9)

Isozymes

Compare fitness of predicted isozymes for: 3.4.11.9

Use Curated BLAST to search for 3.4.11.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBH5 at UniProt or InterPro

Protein Sequence (595 amino acids)

>Shew_0952 peptidase M24 (RefSeq) (Shewanella loihica PV-4)
MTSVTAQRLDAVRSDMLSQTLDAFIVPRADEYLGEYVPERNERLHWLTGFTGSAGMAIVL
KESAAIFIDGRYTVQVKQQVDSAQFDYQSLTDTPQIPWLIAQLSAGARIGYDPRLHTLSW
QQQAEAQCQRAGIELVAVADNPIDRHWQERPAASSAAISLFSEQSAGISSTMKREQIGKA
VAAVGADVALISALDSFCWLLNIRGSDVPRLPVVLGTALLYKNGEMTLFTDLAKLPEGIQ
AHVGAGVSFMAETELEGVLSKFDGVKLLADPDSANAWMQLTAKQAGARLIAGQDPVALPK
AQKNPAELAGLSACHIRDGVAVSRFLAWLDVEVAAKRLYDEGTLADKLESFRLEDPLYRE
PSFDTISAAGANAAMCHYNHNNGTPAMMTMDSIYLVDSGAQYLDGTTDVTRTIAIGEVTD
EQRKMVTLVLKGHIALDQARFPKGTTGQQLDGFARQYLWQHGFDYDHGTGHGVGHFLSVH
EGPQRIAKNSNGVALLPGMVVSNEPGYYRADAFGIRIENLITVQACEALAGAEREMYEFH
ALTLIPIDTRLIDKQLLNDAEINWLNGYHQRVRETLSPLMQGTELDWLLKATEAI