Protein Info for Shew_0935 in Shewanella loihica PV-4

Annotation: peptidase S8 and S53, subtilisin, kexin, sedolisin (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1199 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details transmembrane" amino acids 1176 to 1194 (19 residues), see Phobius details PF00082: Peptidase_S8" amino acids 199 to 675 (477 residues), 170.2 bits, see alignment E=9.4e-54 PF02225: PA" amino acids 467 to 554 (88 residues), 46.7 bits, see alignment 4.4e-16 PF17766: fn3_6" amino acids 729 to 813 (85 residues), 26.7 bits, see alignment 7.6e-10 TIGR03501: GlyGly-CTERM domain" amino acids 1177 to 1198 (22 residues), 19 bits, see alignment (E = 9e-08)

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0935)

Predicted SEED Role

"Serine protease, subtilase family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QBF8 at UniProt or InterPro

Protein Sequence (1199 amino acids)

>Shew_0935 peptidase S8 and S53, subtilisin, kexin, sedolisin (RefSeq) (Shewanella loihica PV-4)
MKSSRRNLLLSALSVAIASACYANPGAASFSDDTKPLQTIIPGQEKLKLERADKQRSDGM
YFVRFKEAPVASYDGSLAGFAATNIQVNQSNKQASGLLNSQSKASLQYRGYLKQQQAKIK
QRLNGKLKRILTPTQEYQLIVNAMAVKLKPGEADIIAKDPEVLSVEPIGLHFIQTSTGPE
FIGAKQVWQGDEIVEATKGEGVIVGVMDTGINANHPSFAEVGADGYQHKNPLGDGQYLGD
CQQYSQFCNGKLIGIISYPELIQYRQDTADSLDDPAYEDLANKVKVGYDFNGHGSHVAST
ASGNILHDVNFYLQVQEEDGTIIAEKSAFEFDAISGVAPHANLVSYQVCDDAGSCYPEFT
LKAIEHAIENGVQVLNYSVGGSAKDPWSSIDAEAFLNAREAGIHVAVAAGNAGPSASTIG
SPGNAPWVTTVAAYTHDLEFKQKSLTNMNGGETPPADMMGFGVTKGVSGKVVLAASVNSD
NAQCTDPFEAGSFDGEIVVCERGTNARVRKGINVKEGGAGGMILINMPDGVDSLHNDNHV
LPAIQLNAADGERLTQWLASGEGHQATIEASETTRNASLGDIAGVFTSRGPNLPYPNIFS
PDIAAPGVDIYAANAEDRLFEGQIGHIPFASLSGTSMATPHVTGAYALLKAAHPDWTPAQ
AQSAFMSTAHQTTYKDDDYDGTLERSDFFDQGAGSLRINQALKAGLLLDIDKAGYLAANP
EMGGDPSALNTSSMVQNQCISNCSWTRTVTATQASSWSAEYEYLNPGFTLEVTPSSFSLN
AGESQVLTIKATANINLVDEWVHGYIKLNNADTSMSDTHLQATIGFKAGQVAEEVSAEMN
NVDNQLVIEDIFTSGSNALQVKGFGLYKAQSFTGSAIGSSNDAERGSPHSNPEVIFSVPT
VVKPYTKRLVVEITDTTSPDMDLYVGIDENGDGMPDAYEMYYSLLCLSGEVDSKERCILE
NPPTGNYWIFAHNYEGRVEDEADEVTLEITHVNYSNQASFDITAPSQVAQDERFDVSLSV
NGYLDDSLSLQPLEAGETYYGLLEMGTTSELKRNIGATLIKVKGLEPVEVPQNTAPVLAN
PIADLQTQLSEQGSAVVSLDLSQVFSDAEGDTLTLSATGVEGITLDGTQLEMNFTASGEY
PIVISASDGELSTETQFTVTVTAAPIVPVEPPSESSGGGSLGYFTLLLLGLSGLRRRQR