Protein Info for Shew_0765 in Shewanella loihica PV-4

Annotation: acriflavin resistance protein (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1049 transmembrane" amino acids 17 to 38 (22 residues), see Phobius details amino acids 335 to 354 (20 residues), see Phobius details amino acids 360 to 379 (20 residues), see Phobius details amino acids 389 to 413 (25 residues), see Phobius details amino acids 434 to 455 (22 residues), see Phobius details amino acids 461 to 480 (20 residues), see Phobius details amino acids 535 to 555 (21 residues), see Phobius details amino acids 863 to 884 (22 residues), see Phobius details amino acids 893 to 913 (21 residues), see Phobius details amino acids 919 to 943 (25 residues), see Phobius details amino acids 963 to 984 (22 residues), see Phobius details amino acids 996 to 1022 (27 residues), see Phobius details PF00873: ACR_tran" amino acids 10 to 1022 (1013 residues), 565.6 bits, see alignment E=1e-173

Best Hits

KEGG orthology group: None (inferred from 100% identity to slo:Shew_0765)

Predicted SEED Role

"Acriflavin resistance protein" in subsystem Multidrug Resistance Efflux Pumps

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAY9 at UniProt or InterPro

Protein Sequence (1049 amino acids)

>Shew_0765 acriflavin resistance protein (RefSeq) (Shewanella loihica PV-4)
METNTNKGIIAWFARNSVAANLLMFALLIGGLFSTVLINKEVFPSFELNYLQITVAYPGA
APQEIEEGINIKIEEAIQDISGIKKVTSVASEGSGSVTIEVEDGFDAQDILDEAKLRIDA
IATFPDNIEKPNIFRIKPENNVIWVSVYGDMNLHEMKELAKSIREEITALPAVTRAQVTG
VRDYEIGIEVSEDKLREYGLSFADVAMAVRNSSIDLPGGSIRAEDGDILLRTKGQAYTGD
DFAKIVVKTRKDGSRIMLPEVANIRDDFEERLEYTRFNGKPAAIIEVLSVDDQNALDISS
QVKAYVEERRATLPASAQLDTWGDLTHYLKGRLNMMLSNMFYGALLVFIILALFLDLRLA
FWVMMGLPVCFLGAMLLMPLEPFSLSINMLTLFAFILVLGIVVDDAIVIGESAYTEIERH
GHSLDNVIKGAHKVAMPATFGVLTTIAAFIPMLMVSGPMAIIWKSIGLVVILCLAFSLVE
SKLILPAHLAHLKPRRPSPNPNLFVRFKTALNNKVQHFIHHSYRSFIGRCIEHRYNVVAT
FVGVLILSVALVASGKVRWVFFPDIPSDFIQVRLEMDVGSSEANTLKVVKEIENALYVMN
DQMEDEYGYPVVKHSFINMGSRTSAFIFAELTKGEDRDVDGVTIADAWRKALPELISVKK
LNINASTNDAGGDISFRLTSSDLEQLSQAADELKQKLRTYEGVYDISDNYSSGSHEIRLA
IKPEAEALGLTLSDLASQVRYGFYGYEAQRILRNKEEVKVMVRYPLEQRRTLGHLENMMI
RTPQGTSVPFSSVADIELGDSYSSITRVDGRRAITVIANANKNVVEPSKVVGEIQKDFLP
YLESKYRHISTTLDGGSADEQSAMIGLIQGFFFAMFTIYALMAIPLKSYSQPLIIMSVIP
FGIIGALFGHFILGLSMSVLSLCGIVALAGVVVNDSLILVDFVNRARAQGLPLKDAAIDA
GCYRFRAIILTSMTTFVGLVPIILERSLQAQIVIPMATSLAFGILFSTVVTLVLVPVLYI
ILNDIRQLTGRVFRWWWQPRSHSVEGEQS