Protein Info for Shew_0709 in Shewanella loihica PV-4

Annotation: catalase/peroxidase HPI (RefSeq)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 756 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR00198: catalase/peroxidase HPI" amino acids 53 to 756 (704 residues), 1070.9 bits, see alignment E=0 PF00141: peroxidase" amino acids 112 to 420 (309 residues), 143.5 bits, see alignment E=5e-46 amino acids 478 to 733 (256 residues), 102.4 bits, see alignment E=1.8e-33

Best Hits

Swiss-Prot: 100% identical to KATG_SHELP: Catalase-peroxidase (katG) from Shewanella loihica (strain ATCC BAA-1088 / PV-4)

KEGG orthology group: K03782, catalase/peroxidase [EC: 1.11.1.6 1.11.1.7] (inferred from 100% identity to slo:Shew_0709)

Predicted SEED Role

"Catalase (EC 1.11.1.6) / Peroxidase (EC 1.11.1.7)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) or Auxin degradation (EC 1.11.1.6, EC 1.11.1.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6 or 1.11.1.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See A3QAT3 at UniProt or InterPro

Protein Sequence (756 amino acids)

>Shew_0709 catalase/peroxidase HPI (RefSeq) (Shewanella loihica PV-4)
MKGKTVNKQTLAALVSALLVFNPAVADEQESAQMTKPKGAAATGTAKAFQPKSKQFWWPD
QLDLSPLRDHDSRSNPYGESFDYAKAFNSLDLDQVKADIDQLLTQSQDWWPADYGNYGPF
FIRMTWHSAGTYRTLDGRGGAGGGQQRFEPLNSWPDNASLDKARRLLWPVKQKYGEALSW
SDLIVLAGNVALENMGFKTFGFAGGRNDDWEPDMVYWGPEVEMLASDREDRDGKLQRPLG
ATHMGLIYVNPEGPKGVPDPLGSAKNIRTAFSRMAMNDEETLALIAGGHTFGKMHGAHKP
KDCLGAEPAAAGIEAQGLGWHNKCGKGHSEDTITSGLEGAWTQAPTKWTSLYLSNLLTYD
WQQTRSPAGAIQWIPTDESVHKAVPDAHVKGKFHAPVMTTADLALKYDPEYRKIAERFLA
DPEEYRLAFAKAWYKLTHRDMGPARNFLGKEVPQGNFIWQDPIDDKTQSRLSAGDIKQLK
KAISKSGLSVAERVRLAWASAASYRQSDMRGGANGARIALAPQKDWTVNNPAETAKVLKT
LEAIRADFNKGAGKRQVSLADLIVLAGASALEQAAKQAGFEVAVPFTPGRGDATQAQTDE
NSFSLLELHADGFRNYFDVNHSYKSPTEMLVDKADQLDLTVPEMTVLVGGLRALDANYQG
AKHGVLTQRPGTLNNDFFVNLLDMSTLWQKSDVDGIYQGLDRSSGKPKWTATSVDLIFGS
NSELRAVAEVYAFDTSKQKFVDDFVAAWVKVMNLDR